RASSF8-ST8SIA1 Fusion FISH Probe
The RASSF8-ST8SIA1 Fusion FISH Probe is used to confirm a fusion of the RASSF8 and ST8SIA1 genes. The fusion of the RASSF8 and ST8SIA1 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RASSF8-ST8SIA1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RASSF8-ST8SIA1-20-RERE | 20 (40 μL) | 200 μL |
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| RASSF8-ST8SIA1-20-REOR | 20 (40 μL) | 200 μL |
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| RASSF8-ST8SIA1-20-REGO | 20 (40 μL) | 200 μL |
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| RASSF8-ST8SIA1-20-REGR | 20 (40 μL) | 200 μL |
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| RASSF8-ST8SIA1-20-REAQ | 20 (40 μL) | 200 μL |
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| RASSF8-ST8SIA1-20-ORRE | 20 (40 μL) | 200 μL |
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| RASSF8-ST8SIA1-20-OROR | 20 (40 μL) | 200 μL |
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| RASSF8-ST8SIA1-20-ORGO | 20 (40 μL) | 200 μL |
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| RASSF8-ST8SIA1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RASSF8-ST8SIA1-20-GORE | 20 (40 μL) | 200 μL |
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| RASSF8-ST8SIA1-20-GOOR | 20 (40 μL) | 200 μL |
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| RASSF8-ST8SIA1-20-GOGO | 20 (40 μL) | 200 μL |
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| RASSF8-ST8SIA1-20-GOGR | 20 (40 μL) | 200 μL |
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| RASSF8-ST8SIA1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RASSF8-ST8SIA1-20-GRRE | 20 (40 μL) | 200 μL |
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| RASSF8-ST8SIA1-20-GROR | 20 (40 μL) | 200 μL |
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| RASSF8-ST8SIA1-20-GRGO | 20 (40 μL) | 200 μL |
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| RASSF8-ST8SIA1-20-GRGR | 20 (40 μL) | 200 μL |
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| RASSF8-ST8SIA1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RASSF8-ST8SIA1-20-AQRE | 20 (40 μL) | 200 μL |
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| RASSF8-ST8SIA1-20-AQOR | 20 (40 μL) | 200 μL |
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| RASSF8-ST8SIA1-20-AQGO | 20 (40 μL) | 200 μL |
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| RASSF8-ST8SIA1-20-AQGR | 20 (40 μL) | 200 μL |
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| RASSF8-ST8SIA1-20-AQAQ | 20 (40 μL) | 200 μL |
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ST8SIA1 Gene Summary
Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2015]
Gene Name: ST8 Alpha-N-acetyl-neuraminide Alpha-2,8-sialyltransferase 1
Chromosome: CHR12: 22346324 -22487648
Locus: 12p12.1
RASSF8 Gene Summary
This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Gene Name: Ras Association Domain Family Member 8
Chromosome: CHR12: 26111963 -26232825
Locus: 12p12.1
Gene Diseases
The RASSF8 ST8SIA1 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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