RASSF6-LEMD3 Fusion FISH Probe
The RASSF6-LEMD3 Fusion FISH Probe is used to confirm a fusion of the RASSF6 and LEMD3 genes. The fusion of the RASSF6 and LEMD3 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RASSF6-LEMD3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RASSF6-LEMD3-20-RERE | 20 (40 μL) | 200 μL |
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| RASSF6-LEMD3-20-REOR | 20 (40 μL) | 200 μL |
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| RASSF6-LEMD3-20-REGO | 20 (40 μL) | 200 μL |
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| RASSF6-LEMD3-20-REGR | 20 (40 μL) | 200 μL |
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| RASSF6-LEMD3-20-REAQ | 20 (40 μL) | 200 μL |
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| RASSF6-LEMD3-20-ORRE | 20 (40 μL) | 200 μL |
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| RASSF6-LEMD3-20-OROR | 20 (40 μL) | 200 μL |
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| RASSF6-LEMD3-20-ORGO | 20 (40 μL) | 200 μL |
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| RASSF6-LEMD3-20-ORAQ | 20 (40 μL) | 200 μL |
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| RASSF6-LEMD3-20-GORE | 20 (40 μL) | 200 μL |
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| RASSF6-LEMD3-20-GOOR | 20 (40 μL) | 200 μL |
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| RASSF6-LEMD3-20-GOGO | 20 (40 μL) | 200 μL |
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| RASSF6-LEMD3-20-GOGR | 20 (40 μL) | 200 μL |
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| RASSF6-LEMD3-20-GOAQ | 20 (40 μL) | 200 μL |
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| RASSF6-LEMD3-20-GRRE | 20 (40 μL) | 200 μL |
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| RASSF6-LEMD3-20-GROR | 20 (40 μL) | 200 μL |
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| RASSF6-LEMD3-20-GRGO | 20 (40 μL) | 200 μL |
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| RASSF6-LEMD3-20-GRGR | 20 (40 μL) | 200 μL |
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| RASSF6-LEMD3-20-GRAQ | 20 (40 μL) | 200 μL |
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| RASSF6-LEMD3-20-AQRE | 20 (40 μL) | 200 μL |
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| RASSF6-LEMD3-20-AQOR | 20 (40 μL) | 200 μL |
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| RASSF6-LEMD3-20-AQGO | 20 (40 μL) | 200 μL |
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| RASSF6-LEMD3-20-AQGR | 20 (40 μL) | 200 μL |
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| RASSF6-LEMD3-20-AQAQ | 20 (40 μL) | 200 μL |
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LEMD3 Gene Summary
This locus encodes a LEM domain-containing protein. The encoded protein functions to antagonize transforming growth factor-beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.[provided by RefSeq, Nov 2009]
Gene Name: LEM Domain Containing 3
Chromosome: CHR12: 65563350 -65642141
Locus: 12q14.3
RASSF6 Gene Summary
This gene encodes a member of the Ras-association domain family (RASSF). Members of this family form the core of a highly conserved tumor suppressor network, the Salvador-Warts-Hippo (SWH) pathway. The protein encoded by this gene is a Ras effector protein that induces apoptosis. A genomic region containing this gene has been linked to susceptibility to viral bronchiolitis. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]
Gene Name: Ras Association Domain Family Member 6
Chromosome: CHR4: 74438861 -74486340
Locus: 4q13.3
Gene Diseases
The RASSF6 LEMD3 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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