RASSF3-ITGA7 Fusion FISH Probe
The RASSF3-ITGA7 Fusion FISH Probe is used to confirm a fusion of the RASSF3 and ITGA7 genes. The fusion of the RASSF3 and ITGA7 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RASSF3-ITGA7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RASSF3-ITGA7-20-RERE | 20 (40 μL) | 200 μL |
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| RASSF3-ITGA7-20-REOR | 20 (40 μL) | 200 μL |
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| RASSF3-ITGA7-20-REGO | 20 (40 μL) | 200 μL |
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| RASSF3-ITGA7-20-REGR | 20 (40 μL) | 200 μL |
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| RASSF3-ITGA7-20-REAQ | 20 (40 μL) | 200 μL |
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| RASSF3-ITGA7-20-ORRE | 20 (40 μL) | 200 μL |
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| RASSF3-ITGA7-20-OROR | 20 (40 μL) | 200 μL |
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| RASSF3-ITGA7-20-ORGO | 20 (40 μL) | 200 μL |
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| RASSF3-ITGA7-20-ORAQ | 20 (40 μL) | 200 μL |
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| RASSF3-ITGA7-20-GORE | 20 (40 μL) | 200 μL |
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| RASSF3-ITGA7-20-GOOR | 20 (40 μL) | 200 μL |
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| RASSF3-ITGA7-20-GOGO | 20 (40 μL) | 200 μL |
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| RASSF3-ITGA7-20-GOGR | 20 (40 μL) | 200 μL |
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| RASSF3-ITGA7-20-GOAQ | 20 (40 μL) | 200 μL |
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| RASSF3-ITGA7-20-GRRE | 20 (40 μL) | 200 μL |
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| RASSF3-ITGA7-20-GROR | 20 (40 μL) | 200 μL |
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| RASSF3-ITGA7-20-GRGO | 20 (40 μL) | 200 μL |
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| RASSF3-ITGA7-20-GRGR | 20 (40 μL) | 200 μL |
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| RASSF3-ITGA7-20-GRAQ | 20 (40 μL) | 200 μL |
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| RASSF3-ITGA7-20-AQRE | 20 (40 μL) | 200 μL |
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| RASSF3-ITGA7-20-AQOR | 20 (40 μL) | 200 μL |
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| RASSF3-ITGA7-20-AQGO | 20 (40 μL) | 200 μL |
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| RASSF3-ITGA7-20-AQGR | 20 (40 μL) | 200 μL |
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| RASSF3-ITGA7-20-AQAQ | 20 (40 μL) | 200 μL |
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ITGA7 Gene Summary
The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Feb 2009]
Gene Name: Integrin Subunit Alpha 7
Chromosome: CHR12: 56078353 -56106089
Locus: 12q13.2
RASSF3 Gene Summary
The RAS oncogene (MIM 190020) is mutated in nearly one-third of all human cancers. Members of the RAS superfamily are plasma membrane GTP-binding proteins that modulate intracellular signal transduction pathways. A subfamily of RAS effectors, including RASSF3, share a RAS association (RA) domain.[supplied by OMIM, Jul 2003]
Gene Name: Ras Association Domain Family Member 3
Chromosome: CHR12: 65004292 -65091347
Locus: 12q14.2
Gene Diseases
The RASSF3 ITGA7 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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