RASGRP1-LRRC4C Fusion FISH Probe
The RASGRP1-LRRC4C Fusion FISH Probe is used to confirm a fusion of the RASGRP1 and LRRC4C genes. The fusion of the RASGRP1 and LRRC4C genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RASGRP1-LRRC4C-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RASGRP1-LRRC4C-20-RERE | 20 (40 μL) | 200 μL |
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| RASGRP1-LRRC4C-20-REOR | 20 (40 μL) | 200 μL |
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| RASGRP1-LRRC4C-20-REGO | 20 (40 μL) | 200 μL |
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| RASGRP1-LRRC4C-20-REGR | 20 (40 μL) | 200 μL |
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| RASGRP1-LRRC4C-20-REAQ | 20 (40 μL) | 200 μL |
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| RASGRP1-LRRC4C-20-ORRE | 20 (40 μL) | 200 μL |
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| RASGRP1-LRRC4C-20-OROR | 20 (40 μL) | 200 μL |
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| RASGRP1-LRRC4C-20-ORGO | 20 (40 μL) | 200 μL |
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| RASGRP1-LRRC4C-20-ORAQ | 20 (40 μL) | 200 μL |
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| RASGRP1-LRRC4C-20-GORE | 20 (40 μL) | 200 μL |
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| RASGRP1-LRRC4C-20-GOOR | 20 (40 μL) | 200 μL |
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| RASGRP1-LRRC4C-20-GOGO | 20 (40 μL) | 200 μL |
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| RASGRP1-LRRC4C-20-GOGR | 20 (40 μL) | 200 μL |
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| RASGRP1-LRRC4C-20-GOAQ | 20 (40 μL) | 200 μL |
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| RASGRP1-LRRC4C-20-GRRE | 20 (40 μL) | 200 μL |
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| RASGRP1-LRRC4C-20-GROR | 20 (40 μL) | 200 μL |
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| RASGRP1-LRRC4C-20-GRGO | 20 (40 μL) | 200 μL |
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| RASGRP1-LRRC4C-20-GRGR | 20 (40 μL) | 200 μL |
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| RASGRP1-LRRC4C-20-GRAQ | 20 (40 μL) | 200 μL |
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| RASGRP1-LRRC4C-20-AQRE | 20 (40 μL) | 200 μL |
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| RASGRP1-LRRC4C-20-AQOR | 20 (40 μL) | 200 μL |
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| RASGRP1-LRRC4C-20-AQGO | 20 (40 μL) | 200 μL |
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| RASGRP1-LRRC4C-20-AQGR | 20 (40 μL) | 200 μL |
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| RASGRP1-LRRC4C-20-AQAQ | 20 (40 μL) | 200 μL |
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RASGRP1 Gene Summary
This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE). [provided by RefSeq, Jul 2008]
Gene Name: RAS Guanyl Releasing Protein 1
Chromosome: CHR15: 38780301 -38857007
Locus: 15q14
LRRC4C Gene Summary
NGL1 is a specific binding partner for netrin G1 (NTNG1; MIM 608818), which is a member of the netrin family of axon guidance molecules (Lin et al., 2003 [PubMed 14595443]).[supplied by OMIM, Mar 2008]
Gene Name: Leucine Rich Repeat Containing 4C
Chromosome: CHR11: 40135752 -40315664
Locus: 11p12
Gene Diseases
The RASGRP1 LRRC4C Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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