RASGRP1-CD47 Fusion FISH Probe
The RASGRP1-CD47 Fusion FISH Probe is used to confirm a fusion of the RASGRP1 and CD47 genes. The fusion of the RASGRP1 and CD47 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RASGRP1-CD47-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RASGRP1-CD47-20-RERE | 20 (40 μL) | 200 μL |
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| RASGRP1-CD47-20-REOR | 20 (40 μL) | 200 μL |
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| RASGRP1-CD47-20-REGO | 20 (40 μL) | 200 μL |
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| RASGRP1-CD47-20-REGR | 20 (40 μL) | 200 μL |
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| RASGRP1-CD47-20-REAQ | 20 (40 μL) | 200 μL |
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| RASGRP1-CD47-20-ORRE | 20 (40 μL) | 200 μL |
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| RASGRP1-CD47-20-OROR | 20 (40 μL) | 200 μL |
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| RASGRP1-CD47-20-ORGO | 20 (40 μL) | 200 μL |
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| RASGRP1-CD47-20-ORAQ | 20 (40 μL) | 200 μL |
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| RASGRP1-CD47-20-GORE | 20 (40 μL) | 200 μL |
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| RASGRP1-CD47-20-GOOR | 20 (40 μL) | 200 μL |
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| RASGRP1-CD47-20-GOGO | 20 (40 μL) | 200 μL |
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| RASGRP1-CD47-20-GOGR | 20 (40 μL) | 200 μL |
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| RASGRP1-CD47-20-GOAQ | 20 (40 μL) | 200 μL |
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| RASGRP1-CD47-20-GRRE | 20 (40 μL) | 200 μL |
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| RASGRP1-CD47-20-GROR | 20 (40 μL) | 200 μL |
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| RASGRP1-CD47-20-GRGO | 20 (40 μL) | 200 μL |
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| RASGRP1-CD47-20-GRGR | 20 (40 μL) | 200 μL |
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| RASGRP1-CD47-20-GRAQ | 20 (40 μL) | 200 μL |
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| RASGRP1-CD47-20-AQRE | 20 (40 μL) | 200 μL |
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| RASGRP1-CD47-20-AQOR | 20 (40 μL) | 200 μL |
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| RASGRP1-CD47-20-AQGO | 20 (40 μL) | 200 μL |
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| RASGRP1-CD47-20-AQGR | 20 (40 μL) | 200 μL |
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| RASGRP1-CD47-20-AQAQ | 20 (40 μL) | 200 μL |
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CD47 Gene Summary
This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]
Gene Name: CD47 Molecule
Chromosome: CHR3: 107761940 -107809935
Locus: 3q13.12
RASGRP1 Gene Summary
This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE). [provided by RefSeq, Jul 2008]
Gene Name: RAS Guanyl Releasing Protein 1
Chromosome: CHR15: 38780301 -38857007
Locus: 15q14
Gene Diseases
The RASGRP1 CD47 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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