RASAL2-SOAT1 Fusion FISH Probe
The RASAL2-SOAT1 Fusion FISH Probe is used to confirm a fusion of the RASAL2 and SOAT1 genes. The fusion of the RASAL2 and SOAT1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RASAL2-SOAT1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RASAL2-SOAT1-20-RERE | 20 (40 μL) | 200 μL |
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| RASAL2-SOAT1-20-REOR | 20 (40 μL) | 200 μL |
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| RASAL2-SOAT1-20-REGO | 20 (40 μL) | 200 μL |
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| RASAL2-SOAT1-20-REGR | 20 (40 μL) | 200 μL |
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| RASAL2-SOAT1-20-REAQ | 20 (40 μL) | 200 μL |
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| RASAL2-SOAT1-20-ORRE | 20 (40 μL) | 200 μL |
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| RASAL2-SOAT1-20-OROR | 20 (40 μL) | 200 μL |
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| RASAL2-SOAT1-20-ORGO | 20 (40 μL) | 200 μL |
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| RASAL2-SOAT1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RASAL2-SOAT1-20-GORE | 20 (40 μL) | 200 μL |
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| RASAL2-SOAT1-20-GOOR | 20 (40 μL) | 200 μL |
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| RASAL2-SOAT1-20-GOGO | 20 (40 μL) | 200 μL |
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| RASAL2-SOAT1-20-GOGR | 20 (40 μL) | 200 μL |
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| RASAL2-SOAT1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RASAL2-SOAT1-20-GRRE | 20 (40 μL) | 200 μL |
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| RASAL2-SOAT1-20-GROR | 20 (40 μL) | 200 μL |
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| RASAL2-SOAT1-20-GRGO | 20 (40 μL) | 200 μL |
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| RASAL2-SOAT1-20-GRGR | 20 (40 μL) | 200 μL |
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| RASAL2-SOAT1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RASAL2-SOAT1-20-AQRE | 20 (40 μL) | 200 μL |
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| RASAL2-SOAT1-20-AQOR | 20 (40 μL) | 200 μL |
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| RASAL2-SOAT1-20-AQGO | 20 (40 μL) | 200 μL |
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| RASAL2-SOAT1-20-AQGR | 20 (40 μL) | 200 μL |
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| RASAL2-SOAT1-20-AQAQ | 20 (40 μL) | 200 μL |
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SOAT1 Gene Summary
The protein encoded by this gene belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. This gene has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011]
Gene Name: Sterol O-acyltransferase 1
Chromosome: CHR1: 179263016 -179324453
Locus: 1q25.2
RASAL2 Gene Summary
This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Gene Name: RAS Protein Activator Like 2
Chromosome: CHR1: 178062863 -178448648
Locus: 1q25.2
Gene Diseases
The RASAL2 SOAT1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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