RASAL2-NUF2 Fusion FISH Probe
The RASAL2-NUF2 Fusion FISH Probe is used to confirm a fusion of the RASAL2 and NUF2 genes. The fusion of the RASAL2 and NUF2 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RASAL2-NUF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RASAL2-NUF2-20-RERE | 20 (40 μL) | 200 μL |
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| RASAL2-NUF2-20-REOR | 20 (40 μL) | 200 μL |
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| RASAL2-NUF2-20-REGO | 20 (40 μL) | 200 μL |
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| RASAL2-NUF2-20-REGR | 20 (40 μL) | 200 μL |
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| RASAL2-NUF2-20-REAQ | 20 (40 μL) | 200 μL |
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| RASAL2-NUF2-20-ORRE | 20 (40 μL) | 200 μL |
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| RASAL2-NUF2-20-OROR | 20 (40 μL) | 200 μL |
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| RASAL2-NUF2-20-ORGO | 20 (40 μL) | 200 μL |
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| RASAL2-NUF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| RASAL2-NUF2-20-GORE | 20 (40 μL) | 200 μL |
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| RASAL2-NUF2-20-GOOR | 20 (40 μL) | 200 μL |
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| RASAL2-NUF2-20-GOGO | 20 (40 μL) | 200 μL |
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| RASAL2-NUF2-20-GOGR | 20 (40 μL) | 200 μL |
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| RASAL2-NUF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| RASAL2-NUF2-20-GRRE | 20 (40 μL) | 200 μL |
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| RASAL2-NUF2-20-GROR | 20 (40 μL) | 200 μL |
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| RASAL2-NUF2-20-GRGO | 20 (40 μL) | 200 μL |
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| RASAL2-NUF2-20-GRGR | 20 (40 μL) | 200 μL |
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| RASAL2-NUF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| RASAL2-NUF2-20-AQRE | 20 (40 μL) | 200 μL |
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| RASAL2-NUF2-20-AQOR | 20 (40 μL) | 200 μL |
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| RASAL2-NUF2-20-AQGO | 20 (40 μL) | 200 μL |
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| RASAL2-NUF2-20-AQGR | 20 (40 μL) | 200 μL |
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| RASAL2-NUF2-20-AQAQ | 20 (40 μL) | 200 μL |
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RASAL2 Gene Summary
This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Gene Name: RAS Protein Activator Like 2
Chromosome: CHR1: 178062863 -178448648
Locus: 1q25.2
NUF2 Gene Summary
This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]
Gene Name: NUF2, NDC80 Kinetochore Complex Component
Chromosome: CHR1: 163291722 -163325553
Locus: 1q23.3
Gene Diseases
The RASAL2 NUF2 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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