RARA-SLC9A3R1 Fusion FISH Probe
The RARA-SLC9A3R1 Fusion FISH Probe is used to confirm a fusion of the RARA and SLC9A3R1 genes. The fusion of the RARA and SLC9A3R1 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RARA-SLC9A3R1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RARA-SLC9A3R1-20-RERE | 20 (40 μL) | 200 μL |
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| RARA-SLC9A3R1-20-REOR | 20 (40 μL) | 200 μL |
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| RARA-SLC9A3R1-20-REGO | 20 (40 μL) | 200 μL |
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| RARA-SLC9A3R1-20-REGR | 20 (40 μL) | 200 μL |
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| RARA-SLC9A3R1-20-REAQ | 20 (40 μL) | 200 μL |
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| RARA-SLC9A3R1-20-ORRE | 20 (40 μL) | 200 μL |
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| RARA-SLC9A3R1-20-OROR | 20 (40 μL) | 200 μL |
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| RARA-SLC9A3R1-20-ORGO | 20 (40 μL) | 200 μL |
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| RARA-SLC9A3R1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RARA-SLC9A3R1-20-GORE | 20 (40 μL) | 200 μL |
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| RARA-SLC9A3R1-20-GOOR | 20 (40 μL) | 200 μL |
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| RARA-SLC9A3R1-20-GOGO | 20 (40 μL) | 200 μL |
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| RARA-SLC9A3R1-20-GOGR | 20 (40 μL) | 200 μL |
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| RARA-SLC9A3R1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RARA-SLC9A3R1-20-GRRE | 20 (40 μL) | 200 μL |
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| RARA-SLC9A3R1-20-GROR | 20 (40 μL) | 200 μL |
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| RARA-SLC9A3R1-20-GRGO | 20 (40 μL) | 200 μL |
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| RARA-SLC9A3R1-20-GRGR | 20 (40 μL) | 200 μL |
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| RARA-SLC9A3R1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RARA-SLC9A3R1-20-AQRE | 20 (40 μL) | 200 μL |
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| RARA-SLC9A3R1-20-AQOR | 20 (40 μL) | 200 μL |
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| RARA-SLC9A3R1-20-AQGO | 20 (40 μL) | 200 μL |
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| RARA-SLC9A3R1-20-AQGR | 20 (40 μL) | 200 μL |
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| RARA-SLC9A3R1-20-AQAQ | 20 (40 μL) | 200 μL |
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RARA Gene Summary
This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.[provided by RefSeq, Sep 2010]
Gene Name: Retinoic Acid Receptor Alpha
Chromosome: CHR17: 38465422 -38513895
Locus: 17q21.2
SLC9A3R1 Gene Summary
This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.[provided by RefSeq, Sep 2009]
Gene Name: SLC9A3 Regulator 1
Chromosome: CHR17: 72744762 -72765499
Locus: 17q25.1
Gene Diseases
The RARA SLC9A3R1 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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