RARA-LTBP1 Fusion FISH Probe
The RARA-LTBP1 Fusion FISH Probe is used to confirm a fusion of the RARA and LTBP1 genes. The fusion of the RARA and LTBP1 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RARA-LTBP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RARA-LTBP1-20-RERE | 20 (40 μL) | 200 μL |
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| RARA-LTBP1-20-REOR | 20 (40 μL) | 200 μL |
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| RARA-LTBP1-20-REGO | 20 (40 μL) | 200 μL |
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| RARA-LTBP1-20-REGR | 20 (40 μL) | 200 μL |
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| RARA-LTBP1-20-REAQ | 20 (40 μL) | 200 μL |
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| RARA-LTBP1-20-ORRE | 20 (40 μL) | 200 μL |
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| RARA-LTBP1-20-OROR | 20 (40 μL) | 200 μL |
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| RARA-LTBP1-20-ORGO | 20 (40 μL) | 200 μL |
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| RARA-LTBP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RARA-LTBP1-20-GORE | 20 (40 μL) | 200 μL |
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| RARA-LTBP1-20-GOOR | 20 (40 μL) | 200 μL |
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| RARA-LTBP1-20-GOGO | 20 (40 μL) | 200 μL |
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| RARA-LTBP1-20-GOGR | 20 (40 μL) | 200 μL |
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| RARA-LTBP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RARA-LTBP1-20-GRRE | 20 (40 μL) | 200 μL |
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| RARA-LTBP1-20-GROR | 20 (40 μL) | 200 μL |
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| RARA-LTBP1-20-GRGO | 20 (40 μL) | 200 μL |
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| RARA-LTBP1-20-GRGR | 20 (40 μL) | 200 μL |
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| RARA-LTBP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RARA-LTBP1-20-AQRE | 20 (40 μL) | 200 μL |
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| RARA-LTBP1-20-AQOR | 20 (40 μL) | 200 μL |
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| RARA-LTBP1-20-AQGO | 20 (40 μL) | 200 μL |
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| RARA-LTBP1-20-AQGR | 20 (40 μL) | 200 μL |
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| RARA-LTBP1-20-AQAQ | 20 (40 μL) | 200 μL |
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LTBP1 Gene Summary
The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins (LTBPs). The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Latent Transforming Growth Factor Beta Binding Protein 1
Chromosome: CHR2: 33172368 -33624575
Locus: 2p22.3
RARA Gene Summary
This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.[provided by RefSeq, Sep 2010]
Gene Name: Retinoic Acid Receptor Alpha
Chromosome: CHR17: 38465422 -38513895
Locus: 17q21.2
Gene Diseases
The RARA LTBP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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