RAPGEF5-CFDP1 Fusion FISH Probe
The RAPGEF5-CFDP1 Fusion FISH Probe is used to confirm a fusion of the RAPGEF5 and CFDP1 genes. The fusion of the RAPGEF5 and CFDP1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RAPGEF5-CFDP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RAPGEF5-CFDP1-20-RERE | 20 (40 μL) | 200 μL |
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| RAPGEF5-CFDP1-20-REOR | 20 (40 μL) | 200 μL |
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| RAPGEF5-CFDP1-20-REGO | 20 (40 μL) | 200 μL |
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| RAPGEF5-CFDP1-20-REGR | 20 (40 μL) | 200 μL |
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| RAPGEF5-CFDP1-20-REAQ | 20 (40 μL) | 200 μL |
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| RAPGEF5-CFDP1-20-ORRE | 20 (40 μL) | 200 μL |
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| RAPGEF5-CFDP1-20-OROR | 20 (40 μL) | 200 μL |
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| RAPGEF5-CFDP1-20-ORGO | 20 (40 μL) | 200 μL |
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| RAPGEF5-CFDP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RAPGEF5-CFDP1-20-GORE | 20 (40 μL) | 200 μL |
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| RAPGEF5-CFDP1-20-GOOR | 20 (40 μL) | 200 μL |
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| RAPGEF5-CFDP1-20-GOGO | 20 (40 μL) | 200 μL |
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| RAPGEF5-CFDP1-20-GOGR | 20 (40 μL) | 200 μL |
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| RAPGEF5-CFDP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RAPGEF5-CFDP1-20-GRRE | 20 (40 μL) | 200 μL |
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| RAPGEF5-CFDP1-20-GROR | 20 (40 μL) | 200 μL |
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| RAPGEF5-CFDP1-20-GRGO | 20 (40 μL) | 200 μL |
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| RAPGEF5-CFDP1-20-GRGR | 20 (40 μL) | 200 μL |
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| RAPGEF5-CFDP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RAPGEF5-CFDP1-20-AQRE | 20 (40 μL) | 200 μL |
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| RAPGEF5-CFDP1-20-AQOR | 20 (40 μL) | 200 μL |
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| RAPGEF5-CFDP1-20-AQGO | 20 (40 μL) | 200 μL |
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| RAPGEF5-CFDP1-20-AQGR | 20 (40 μL) | 200 μL |
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| RAPGEF5-CFDP1-20-AQAQ | 20 (40 μL) | 200 μL |
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RAPGEF5 Gene Summary
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008]
Gene Name: Rap Guanine Nucleotide Exchange Factor 5
Chromosome: CHR7: 22157907 -22396533
Locus: 7p15.3
CFDP1 Gene Summary
The Craniofacial Development Protein 1 (CFDP1) gene is located on chr16 :75327607-75467387 at 16q23.1.
Gene Name: Craniofacial Development Protein 1
Chromosome: CHR16: 75327607 -75467387
Locus: 16q23.1
Gene Diseases
The RAPGEF5 CFDP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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