RAPGEF2-RAB3IP Fusion FISH Probe
The RAPGEF2-RAB3IP Fusion FISH Probe is used to confirm a fusion of the RAPGEF2 and RAB3IP genes. The fusion of the RAPGEF2 and RAB3IP genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RAPGEF2-RAB3IP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RAPGEF2-RAB3IP-20-RERE | 20 (40 μL) | 200 μL |
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| RAPGEF2-RAB3IP-20-REOR | 20 (40 μL) | 200 μL |
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| RAPGEF2-RAB3IP-20-REGO | 20 (40 μL) | 200 μL |
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| RAPGEF2-RAB3IP-20-REGR | 20 (40 μL) | 200 μL |
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| RAPGEF2-RAB3IP-20-REAQ | 20 (40 μL) | 200 μL |
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| RAPGEF2-RAB3IP-20-ORRE | 20 (40 μL) | 200 μL |
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| RAPGEF2-RAB3IP-20-OROR | 20 (40 μL) | 200 μL |
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| RAPGEF2-RAB3IP-20-ORGO | 20 (40 μL) | 200 μL |
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| RAPGEF2-RAB3IP-20-ORAQ | 20 (40 μL) | 200 μL |
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| RAPGEF2-RAB3IP-20-GORE | 20 (40 μL) | 200 μL |
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| RAPGEF2-RAB3IP-20-GOOR | 20 (40 μL) | 200 μL |
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| RAPGEF2-RAB3IP-20-GOGO | 20 (40 μL) | 200 μL |
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| RAPGEF2-RAB3IP-20-GOGR | 20 (40 μL) | 200 μL |
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| RAPGEF2-RAB3IP-20-GOAQ | 20 (40 μL) | 200 μL |
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| RAPGEF2-RAB3IP-20-GRRE | 20 (40 μL) | 200 μL |
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| RAPGEF2-RAB3IP-20-GROR | 20 (40 μL) | 200 μL |
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| RAPGEF2-RAB3IP-20-GRGO | 20 (40 μL) | 200 μL |
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| RAPGEF2-RAB3IP-20-GRGR | 20 (40 μL) | 200 μL |
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| RAPGEF2-RAB3IP-20-GRAQ | 20 (40 μL) | 200 μL |
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| RAPGEF2-RAB3IP-20-AQRE | 20 (40 μL) | 200 μL |
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| RAPGEF2-RAB3IP-20-AQOR | 20 (40 μL) | 200 μL |
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| RAPGEF2-RAB3IP-20-AQGO | 20 (40 μL) | 200 μL |
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| RAPGEF2-RAB3IP-20-AQGR | 20 (40 μL) | 200 μL |
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| RAPGEF2-RAB3IP-20-AQAQ | 20 (40 μL) | 200 μL |
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RAPGEF2 Gene Summary
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF2, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008]
Gene Name: Rap Guanine Nucleotide Exchange Factor 2
Chromosome: CHR4: 160188997 -160281301
Locus: 4q32.1
RAB3IP Gene Summary
The RAB3A Interacting Protein (RAB3IP) gene is located on chr12 :70132630-70216984 at 12q15.
Gene Name: RAB3A Interacting Protein
Chromosome: CHR12: 70132630 -70216984
Locus: 12q15
Gene Diseases
The RAPGEF2 RAB3IP Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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