RAPGEF2-C4ORF45 Fusion FISH Probe
The RAPGEF2-C4ORF45 Fusion FISH Probe is used to confirm a fusion of the RAPGEF2 and C4ORF45 genes. The fusion of the RAPGEF2 and C4ORF45 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RAPGEF2-C4ORF45-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RAPGEF2-C4ORF45-20-RERE | 20 (40 μL) | 200 μL |
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| RAPGEF2-C4ORF45-20-REOR | 20 (40 μL) | 200 μL |
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| RAPGEF2-C4ORF45-20-REGO | 20 (40 μL) | 200 μL |
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| RAPGEF2-C4ORF45-20-REGR | 20 (40 μL) | 200 μL |
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| RAPGEF2-C4ORF45-20-REAQ | 20 (40 μL) | 200 μL |
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| RAPGEF2-C4ORF45-20-ORRE | 20 (40 μL) | 200 μL |
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| RAPGEF2-C4ORF45-20-OROR | 20 (40 μL) | 200 μL |
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| RAPGEF2-C4ORF45-20-ORGO | 20 (40 μL) | 200 μL |
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| RAPGEF2-C4ORF45-20-ORAQ | 20 (40 μL) | 200 μL |
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| RAPGEF2-C4ORF45-20-GORE | 20 (40 μL) | 200 μL |
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| RAPGEF2-C4ORF45-20-GOOR | 20 (40 μL) | 200 μL |
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| RAPGEF2-C4ORF45-20-GOGO | 20 (40 μL) | 200 μL |
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| RAPGEF2-C4ORF45-20-GOGR | 20 (40 μL) | 200 μL |
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| RAPGEF2-C4ORF45-20-GOAQ | 20 (40 μL) | 200 μL |
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| RAPGEF2-C4ORF45-20-GRRE | 20 (40 μL) | 200 μL |
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| RAPGEF2-C4ORF45-20-GROR | 20 (40 μL) | 200 μL |
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| RAPGEF2-C4ORF45-20-GRGO | 20 (40 μL) | 200 μL |
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| RAPGEF2-C4ORF45-20-GRGR | 20 (40 μL) | 200 μL |
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| RAPGEF2-C4ORF45-20-GRAQ | 20 (40 μL) | 200 μL |
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| RAPGEF2-C4ORF45-20-AQRE | 20 (40 μL) | 200 μL |
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| RAPGEF2-C4ORF45-20-AQOR | 20 (40 μL) | 200 μL |
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| RAPGEF2-C4ORF45-20-AQGO | 20 (40 μL) | 200 μL |
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| RAPGEF2-C4ORF45-20-AQGR | 20 (40 μL) | 200 μL |
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| RAPGEF2-C4ORF45-20-AQAQ | 20 (40 μL) | 200 μL |
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RAPGEF2 Gene Summary
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF2, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008]
Gene Name: Rap Guanine Nucleotide Exchange Factor 2
Chromosome: CHR4: 160188997 -160281301
Locus: 4q32.1
C4orf45 Gene Summary
The Chromosome 4 Open Reading Frame 45 (C4orf45) gene is located on chr4 :159814683-159956333 at 4q32.1.
Gene Name: Chromosome 4 Open Reading Frame 45
Chromosome: CHR4: 159814683 -159956333
Locus: 4q32.1
Gene Diseases
The RAPGEF2 C4ORF45 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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