RAPGEF1-REXO4 Fusion FISH Probe
The RAPGEF1-REXO4 Fusion FISH Probe is used to confirm a fusion of the RAPGEF1 and REXO4 genes. The fusion of the RAPGEF1 and REXO4 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RAPGEF1-REXO4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RAPGEF1-REXO4-20-RERE | 20 (40 μL) | 200 μL |
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| RAPGEF1-REXO4-20-REOR | 20 (40 μL) | 200 μL |
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| RAPGEF1-REXO4-20-REGO | 20 (40 μL) | 200 μL |
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| RAPGEF1-REXO4-20-REGR | 20 (40 μL) | 200 μL |
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| RAPGEF1-REXO4-20-REAQ | 20 (40 μL) | 200 μL |
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| RAPGEF1-REXO4-20-ORRE | 20 (40 μL) | 200 μL |
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| RAPGEF1-REXO4-20-OROR | 20 (40 μL) | 200 μL |
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| RAPGEF1-REXO4-20-ORGO | 20 (40 μL) | 200 μL |
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| RAPGEF1-REXO4-20-ORAQ | 20 (40 μL) | 200 μL |
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| RAPGEF1-REXO4-20-GORE | 20 (40 μL) | 200 μL |
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| RAPGEF1-REXO4-20-GOOR | 20 (40 μL) | 200 μL |
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| RAPGEF1-REXO4-20-GOGO | 20 (40 μL) | 200 μL |
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| RAPGEF1-REXO4-20-GOGR | 20 (40 μL) | 200 μL |
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| RAPGEF1-REXO4-20-GOAQ | 20 (40 μL) | 200 μL |
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| RAPGEF1-REXO4-20-GRRE | 20 (40 μL) | 200 μL |
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| RAPGEF1-REXO4-20-GROR | 20 (40 μL) | 200 μL |
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| RAPGEF1-REXO4-20-GRGO | 20 (40 μL) | 200 μL |
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| RAPGEF1-REXO4-20-GRGR | 20 (40 μL) | 200 μL |
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| RAPGEF1-REXO4-20-GRAQ | 20 (40 μL) | 200 μL |
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| RAPGEF1-REXO4-20-AQRE | 20 (40 μL) | 200 μL |
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| RAPGEF1-REXO4-20-AQOR | 20 (40 μL) | 200 μL |
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| RAPGEF1-REXO4-20-AQGO | 20 (40 μL) | 200 μL |
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| RAPGEF1-REXO4-20-AQGR | 20 (40 μL) | 200 μL |
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| RAPGEF1-REXO4-20-AQAQ | 20 (40 μL) | 200 μL |
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RAPGEF1 Gene Summary
This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Rap Guanine Nucleotide Exchange Factor 1
Chromosome: CHR9: 134452156 -134612925
Locus: 9q34.13
REXO4 Gene Summary
The REX4 Homolog, 3'-5' Exonuclease (REXO4) gene is located on chr9 :136271185-136283164 at 9q34.2.
Gene Name: REX4 Homolog, 3'-5' Exonuclease
Chromosome: CHR9: 136271185 -136283164
Locus: 9q34.2
Gene Diseases
The RAPGEF1 REXO4 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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