RAP1B-SNUPN Fusion FISH Probe
The RAP1B-SNUPN Fusion FISH Probe is used to confirm a fusion of the RAP1B and SNUPN genes. The fusion of the RAP1B and SNUPN genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RAP1B-SNUPN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RAP1B-SNUPN-20-RERE | 20 (40 μL) | 200 μL |
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| RAP1B-SNUPN-20-REOR | 20 (40 μL) | 200 μL |
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| RAP1B-SNUPN-20-REGO | 20 (40 μL) | 200 μL |
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| RAP1B-SNUPN-20-REGR | 20 (40 μL) | 200 μL |
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| RAP1B-SNUPN-20-REAQ | 20 (40 μL) | 200 μL |
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| RAP1B-SNUPN-20-ORRE | 20 (40 μL) | 200 μL |
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| RAP1B-SNUPN-20-OROR | 20 (40 μL) | 200 μL |
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| RAP1B-SNUPN-20-ORGO | 20 (40 μL) | 200 μL |
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| RAP1B-SNUPN-20-ORAQ | 20 (40 μL) | 200 μL |
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| RAP1B-SNUPN-20-GORE | 20 (40 μL) | 200 μL |
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| RAP1B-SNUPN-20-GOOR | 20 (40 μL) | 200 μL |
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| RAP1B-SNUPN-20-GOGO | 20 (40 μL) | 200 μL |
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| RAP1B-SNUPN-20-GOGR | 20 (40 μL) | 200 μL |
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| RAP1B-SNUPN-20-GOAQ | 20 (40 μL) | 200 μL |
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| RAP1B-SNUPN-20-GRRE | 20 (40 μL) | 200 μL |
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| RAP1B-SNUPN-20-GROR | 20 (40 μL) | 200 μL |
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| RAP1B-SNUPN-20-GRGO | 20 (40 μL) | 200 μL |
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| RAP1B-SNUPN-20-GRGR | 20 (40 μL) | 200 μL |
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| RAP1B-SNUPN-20-GRAQ | 20 (40 μL) | 200 μL |
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| RAP1B-SNUPN-20-AQRE | 20 (40 μL) | 200 μL |
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| RAP1B-SNUPN-20-AQOR | 20 (40 μL) | 200 μL |
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| RAP1B-SNUPN-20-AQGO | 20 (40 μL) | 200 μL |
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| RAP1B-SNUPN-20-AQGR | 20 (40 μL) | 200 μL |
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| RAP1B-SNUPN-20-AQAQ | 20 (40 μL) | 200 μL |
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RAP1B Gene Summary
This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9. [provided by RefSeq, Oct 2011]
Gene Name: RAP1B, Member Of RAS Oncogene Family
Chromosome: CHR12: 69004651 -69054374
Locus: 12q15
SNUPN Gene Summary
The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Snurportin 1
Chromosome: CHR15: 75890423 -75918719
Locus: 15q24.2
Gene Diseases
The RAP1B SNUPN Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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