RAP1B-CSAD Fusion FISH Probe
The RAP1B-CSAD Fusion FISH Probe is used to confirm a fusion of the RAP1B and CSAD genes. The fusion of the RAP1B and CSAD genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RAP1B-CSAD-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RAP1B-CSAD-20-RERE | 20 (40 μL) | 200 μL |
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| RAP1B-CSAD-20-REOR | 20 (40 μL) | 200 μL |
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| RAP1B-CSAD-20-REGO | 20 (40 μL) | 200 μL |
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| RAP1B-CSAD-20-REGR | 20 (40 μL) | 200 μL |
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| RAP1B-CSAD-20-REAQ | 20 (40 μL) | 200 μL |
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| RAP1B-CSAD-20-ORRE | 20 (40 μL) | 200 μL |
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| RAP1B-CSAD-20-OROR | 20 (40 μL) | 200 μL |
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| RAP1B-CSAD-20-ORGO | 20 (40 μL) | 200 μL |
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| RAP1B-CSAD-20-ORAQ | 20 (40 μL) | 200 μL |
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| RAP1B-CSAD-20-GORE | 20 (40 μL) | 200 μL |
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| RAP1B-CSAD-20-GOOR | 20 (40 μL) | 200 μL |
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| RAP1B-CSAD-20-GOGO | 20 (40 μL) | 200 μL |
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| RAP1B-CSAD-20-GOGR | 20 (40 μL) | 200 μL |
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| RAP1B-CSAD-20-GOAQ | 20 (40 μL) | 200 μL |
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| RAP1B-CSAD-20-GRRE | 20 (40 μL) | 200 μL |
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| RAP1B-CSAD-20-GROR | 20 (40 μL) | 200 μL |
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| RAP1B-CSAD-20-GRGO | 20 (40 μL) | 200 μL |
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| RAP1B-CSAD-20-GRGR | 20 (40 μL) | 200 μL |
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| RAP1B-CSAD-20-GRAQ | 20 (40 μL) | 200 μL |
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| RAP1B-CSAD-20-AQRE | 20 (40 μL) | 200 μL |
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| RAP1B-CSAD-20-AQOR | 20 (40 μL) | 200 μL |
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| RAP1B-CSAD-20-AQGO | 20 (40 μL) | 200 μL |
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| RAP1B-CSAD-20-AQGR | 20 (40 μL) | 200 μL |
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| RAP1B-CSAD-20-AQAQ | 20 (40 μL) | 200 μL |
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RAP1B Gene Summary
This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9. [provided by RefSeq, Oct 2011]
Gene Name: RAP1B, Member Of RAS Oncogene Family
Chromosome: CHR12: 69004651 -69054374
Locus: 12q15
CSAD Gene Summary
This gene encodes a member of the group 2 decarboxylase family. A similar protein in rodents plays a role in multiple biological processes as the rate-limiting enzyme in taurine biosynthesis, catalyzing the decarboxylation of cysteinesulfinate to hypotaurine. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Gene Name: Cysteine Sulfinic Acid Decarboxylase
Chromosome: CHR12: 53551446 -53574430
Locus: 12q13.13
Gene Diseases
The RAP1B CSAD Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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