RANBP3-RFX2 Fusion FISH Probe
The RANBP3-RFX2 Fusion FISH Probe is used to confirm a fusion of the RANBP3 and RFX2 genes. The fusion of the RANBP3 and RFX2 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RANBP3-RFX2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RANBP3-RFX2-20-RERE | 20 (40 μL) | 200 μL |
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| RANBP3-RFX2-20-REOR | 20 (40 μL) | 200 μL |
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| RANBP3-RFX2-20-REGO | 20 (40 μL) | 200 μL |
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| RANBP3-RFX2-20-REGR | 20 (40 μL) | 200 μL |
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| RANBP3-RFX2-20-REAQ | 20 (40 μL) | 200 μL |
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| RANBP3-RFX2-20-ORRE | 20 (40 μL) | 200 μL |
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| RANBP3-RFX2-20-OROR | 20 (40 μL) | 200 μL |
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| RANBP3-RFX2-20-ORGO | 20 (40 μL) | 200 μL |
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| RANBP3-RFX2-20-ORAQ | 20 (40 μL) | 200 μL |
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| RANBP3-RFX2-20-GORE | 20 (40 μL) | 200 μL |
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| RANBP3-RFX2-20-GOOR | 20 (40 μL) | 200 μL |
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| RANBP3-RFX2-20-GOGO | 20 (40 μL) | 200 μL |
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| RANBP3-RFX2-20-GOGR | 20 (40 μL) | 200 μL |
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| RANBP3-RFX2-20-GOAQ | 20 (40 μL) | 200 μL |
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| RANBP3-RFX2-20-GRRE | 20 (40 μL) | 200 μL |
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| RANBP3-RFX2-20-GROR | 20 (40 μL) | 200 μL |
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| RANBP3-RFX2-20-GRGO | 20 (40 μL) | 200 μL |
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| RANBP3-RFX2-20-GRGR | 20 (40 μL) | 200 μL |
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| RANBP3-RFX2-20-GRAQ | 20 (40 μL) | 200 μL |
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| RANBP3-RFX2-20-AQRE | 20 (40 μL) | 200 μL |
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| RANBP3-RFX2-20-AQOR | 20 (40 μL) | 200 μL |
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| RANBP3-RFX2-20-AQGO | 20 (40 μL) | 200 μL |
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| RANBP3-RFX2-20-AQGR | 20 (40 μL) | 200 μL |
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| RANBP3-RFX2-20-AQAQ | 20 (40 μL) | 200 μL |
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RFX2 Gene Summary
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008]
Gene Name: Regulatory Factor X2
Chromosome: CHR19: 5993174 -6110664
Locus: 19p13.3
RANBP3 Gene Summary
This gene encodes a protein with a RanBD1 domain that is found in both the nucleus and cytoplasm. This protein plays a role in nuclear export as part of a heteromeric complex. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: RAN Binding Protein 3
Chromosome: CHR19: 5916151 -5978320
Locus: 19p13.3
Gene Diseases
The RANBP3 RFX2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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