RANBP17-GABRP Fusion FISH Probe
The RANBP17-GABRP Fusion FISH Probe is used to confirm a fusion of the RANBP17 and GABRP genes. The fusion of the RANBP17 and GABRP genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RANBP17-GABRP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RANBP17-GABRP-20-RERE | 20 (40 μL) | 200 μL |
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| RANBP17-GABRP-20-REOR | 20 (40 μL) | 200 μL |
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| RANBP17-GABRP-20-REGO | 20 (40 μL) | 200 μL |
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| RANBP17-GABRP-20-REGR | 20 (40 μL) | 200 μL |
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| RANBP17-GABRP-20-REAQ | 20 (40 μL) | 200 μL |
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| RANBP17-GABRP-20-ORRE | 20 (40 μL) | 200 μL |
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| RANBP17-GABRP-20-OROR | 20 (40 μL) | 200 μL |
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| RANBP17-GABRP-20-ORGO | 20 (40 μL) | 200 μL |
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| RANBP17-GABRP-20-ORAQ | 20 (40 μL) | 200 μL |
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| RANBP17-GABRP-20-GORE | 20 (40 μL) | 200 μL |
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| RANBP17-GABRP-20-GOOR | 20 (40 μL) | 200 μL |
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| RANBP17-GABRP-20-GOGO | 20 (40 μL) | 200 μL |
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| RANBP17-GABRP-20-GOGR | 20 (40 μL) | 200 μL |
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| RANBP17-GABRP-20-GOAQ | 20 (40 μL) | 200 μL |
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| RANBP17-GABRP-20-GRRE | 20 (40 μL) | 200 μL |
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| RANBP17-GABRP-20-GROR | 20 (40 μL) | 200 μL |
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| RANBP17-GABRP-20-GRGO | 20 (40 μL) | 200 μL |
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| RANBP17-GABRP-20-GRGR | 20 (40 μL) | 200 μL |
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| RANBP17-GABRP-20-GRAQ | 20 (40 μL) | 200 μL |
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| RANBP17-GABRP-20-AQRE | 20 (40 μL) | 200 μL |
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| RANBP17-GABRP-20-AQOR | 20 (40 μL) | 200 μL |
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| RANBP17-GABRP-20-AQGO | 20 (40 μL) | 200 μL |
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| RANBP17-GABRP-20-AQGR | 20 (40 μL) | 200 μL |
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| RANBP17-GABRP-20-AQAQ | 20 (40 μL) | 200 μL |
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GABRP Gene Summary
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. The subunit encoded by this gene is expressed in several non-neuronal tissues including the uterus and ovaries. This subunit can assemble with known GABA A receptor subunits, and the presence of this subunit alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
Gene Name: Gamma-aminobutyric Acid Type A Receptor Pi Subunit
Chromosome: CHR5: 170210722 -170241050
Locus: 5q35.1
RANBP17 Gene Summary
The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002]
Gene Name: RAN Binding Protein 17
Chromosome: CHR5: 170288895 -170727019
Locus: 5q35.1
Gene Diseases
The RANBP17 GABRP Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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