RALGPS1-LMX1B Fusion FISH Probe
The RALGPS1-LMX1B Fusion FISH Probe is used to confirm a fusion of the RALGPS1 and LMX1B genes. The fusion of the RALGPS1 and LMX1B genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RALGPS1-LMX1B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RALGPS1-LMX1B-20-RERE | 20 (40 μL) | 200 μL |
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| RALGPS1-LMX1B-20-REOR | 20 (40 μL) | 200 μL |
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| RALGPS1-LMX1B-20-REGO | 20 (40 μL) | 200 μL |
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| RALGPS1-LMX1B-20-REGR | 20 (40 μL) | 200 μL |
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| RALGPS1-LMX1B-20-REAQ | 20 (40 μL) | 200 μL |
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| RALGPS1-LMX1B-20-ORRE | 20 (40 μL) | 200 μL |
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| RALGPS1-LMX1B-20-OROR | 20 (40 μL) | 200 μL |
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| RALGPS1-LMX1B-20-ORGO | 20 (40 μL) | 200 μL |
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| RALGPS1-LMX1B-20-ORAQ | 20 (40 μL) | 200 μL |
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| RALGPS1-LMX1B-20-GORE | 20 (40 μL) | 200 μL |
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| RALGPS1-LMX1B-20-GOOR | 20 (40 μL) | 200 μL |
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| RALGPS1-LMX1B-20-GOGO | 20 (40 μL) | 200 μL |
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| RALGPS1-LMX1B-20-GOGR | 20 (40 μL) | 200 μL |
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| RALGPS1-LMX1B-20-GOAQ | 20 (40 μL) | 200 μL |
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| RALGPS1-LMX1B-20-GRRE | 20 (40 μL) | 200 μL |
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| RALGPS1-LMX1B-20-GROR | 20 (40 μL) | 200 μL |
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| RALGPS1-LMX1B-20-GRGO | 20 (40 μL) | 200 μL |
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| RALGPS1-LMX1B-20-GRGR | 20 (40 μL) | 200 μL |
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| RALGPS1-LMX1B-20-GRAQ | 20 (40 μL) | 200 μL |
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| RALGPS1-LMX1B-20-AQRE | 20 (40 μL) | 200 μL |
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| RALGPS1-LMX1B-20-AQOR | 20 (40 μL) | 200 μL |
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| RALGPS1-LMX1B-20-AQGO | 20 (40 μL) | 200 μL |
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| RALGPS1-LMX1B-20-AQGR | 20 (40 μL) | 200 μL |
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| RALGPS1-LMX1B-20-AQAQ | 20 (40 μL) | 200 μL |
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LMX1B Gene Summary
This gene encodes a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains, 1 homeodomain, and a C-terminal glutamine-rich domain. It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail-patella syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Gene Name: LIM Homeobox Transcription Factor 1 Beta
Chromosome: CHR9: 129376721 -129463311
Locus: 9q33.3
RALGPS1 Gene Summary
The Ral GEF With PH Domain And SH3 Binding Motif 1 (RALGPS1) gene is located on chr9 :129677052-129985445 at 9q33.3.
Gene Name: Ral GEF With PH Domain And SH3 Binding Motif 1
Chromosome: CHR9: 129677052 -129985445
Locus: 9q33.3
Gene Diseases
The RALGPS1 LMX1B Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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