RALGAPB-KCNB1 Fusion FISH Probe
The RALGAPB-KCNB1 Fusion FISH Probe is used to confirm a fusion of the RALGAPB and KCNB1 genes. The fusion of the RALGAPB and KCNB1 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RALGAPB-KCNB1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RALGAPB-KCNB1-20-RERE | 20 (40 μL) | 200 μL |
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| RALGAPB-KCNB1-20-REOR | 20 (40 μL) | 200 μL |
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| RALGAPB-KCNB1-20-REGO | 20 (40 μL) | 200 μL |
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| RALGAPB-KCNB1-20-REGR | 20 (40 μL) | 200 μL |
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| RALGAPB-KCNB1-20-REAQ | 20 (40 μL) | 200 μL |
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| RALGAPB-KCNB1-20-ORRE | 20 (40 μL) | 200 μL |
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| RALGAPB-KCNB1-20-OROR | 20 (40 μL) | 200 μL |
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| RALGAPB-KCNB1-20-ORGO | 20 (40 μL) | 200 μL |
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| RALGAPB-KCNB1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RALGAPB-KCNB1-20-GORE | 20 (40 μL) | 200 μL |
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| RALGAPB-KCNB1-20-GOOR | 20 (40 μL) | 200 μL |
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| RALGAPB-KCNB1-20-GOGO | 20 (40 μL) | 200 μL |
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| RALGAPB-KCNB1-20-GOGR | 20 (40 μL) | 200 μL |
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| RALGAPB-KCNB1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RALGAPB-KCNB1-20-GRRE | 20 (40 μL) | 200 μL |
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| RALGAPB-KCNB1-20-GROR | 20 (40 μL) | 200 μL |
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| RALGAPB-KCNB1-20-GRGO | 20 (40 μL) | 200 μL |
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| RALGAPB-KCNB1-20-GRGR | 20 (40 μL) | 200 μL |
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| RALGAPB-KCNB1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RALGAPB-KCNB1-20-AQRE | 20 (40 μL) | 200 μL |
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| RALGAPB-KCNB1-20-AQOR | 20 (40 μL) | 200 μL |
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| RALGAPB-KCNB1-20-AQGO | 20 (40 μL) | 200 μL |
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| RALGAPB-KCNB1-20-AQGR | 20 (40 μL) | 200 μL |
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| RALGAPB-KCNB1-20-AQAQ | 20 (40 μL) | 200 μL |
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KCNB1 Gene Summary
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. [provided by RefSeq, Jul 2008]
Gene Name: Potassium Voltage-gated Channel Subfamily B Member 1
Chromosome: CHR20: 47988504 -48099181
Locus: 20q13.13
RALGAPB Gene Summary
The Ral GTPase Activating Protein Non-catalytic Beta Subunit (RALGAPB) gene is located on chr20 :37101485-37207504 at 20q11.23.
Gene Name: Ral GTPase Activating Protein Non-catalytic Beta Subunit
Chromosome: CHR20: 37101485 -37207504
Locus: 20q11.23
Gene Diseases
The RALGAPB KCNB1 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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