RALGAPB-CTCFL Fusion FISH Probe
The RALGAPB-CTCFL Fusion FISH Probe is used to confirm a fusion of the RALGAPB and CTCFL genes. The fusion of the RALGAPB and CTCFL genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RALGAPB-CTCFL-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RALGAPB-CTCFL-20-RERE | 20 (40 μL) | 200 μL |
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| RALGAPB-CTCFL-20-REOR | 20 (40 μL) | 200 μL |
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| RALGAPB-CTCFL-20-REGO | 20 (40 μL) | 200 μL |
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| RALGAPB-CTCFL-20-REGR | 20 (40 μL) | 200 μL |
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| RALGAPB-CTCFL-20-REAQ | 20 (40 μL) | 200 μL |
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| RALGAPB-CTCFL-20-ORRE | 20 (40 μL) | 200 μL |
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| RALGAPB-CTCFL-20-OROR | 20 (40 μL) | 200 μL |
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| RALGAPB-CTCFL-20-ORGO | 20 (40 μL) | 200 μL |
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| RALGAPB-CTCFL-20-ORAQ | 20 (40 μL) | 200 μL |
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| RALGAPB-CTCFL-20-GORE | 20 (40 μL) | 200 μL |
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| RALGAPB-CTCFL-20-GOOR | 20 (40 μL) | 200 μL |
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| RALGAPB-CTCFL-20-GOGO | 20 (40 μL) | 200 μL |
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| RALGAPB-CTCFL-20-GOGR | 20 (40 μL) | 200 μL |
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| RALGAPB-CTCFL-20-GOAQ | 20 (40 μL) | 200 μL |
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| RALGAPB-CTCFL-20-GRRE | 20 (40 μL) | 200 μL |
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| RALGAPB-CTCFL-20-GROR | 20 (40 μL) | 200 μL |
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| RALGAPB-CTCFL-20-GRGO | 20 (40 μL) | 200 μL |
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| RALGAPB-CTCFL-20-GRGR | 20 (40 μL) | 200 μL |
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| RALGAPB-CTCFL-20-GRAQ | 20 (40 μL) | 200 μL |
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| RALGAPB-CTCFL-20-AQRE | 20 (40 μL) | 200 μL |
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| RALGAPB-CTCFL-20-AQOR | 20 (40 μL) | 200 μL |
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| RALGAPB-CTCFL-20-AQGO | 20 (40 μL) | 200 μL |
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| RALGAPB-CTCFL-20-AQGR | 20 (40 μL) | 200 μL |
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| RALGAPB-CTCFL-20-AQAQ | 20 (40 μL) | 200 μL |
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RALGAPB Gene Summary
The Ral GTPase Activating Protein Non-catalytic Beta Subunit (RALGAPB) gene is located on chr20 :37101485-37207504 at 20q11.23.
Gene Name: Ral GTPase Activating Protein Non-catalytic Beta Subunit
Chromosome: CHR20: 37101485 -37207504
Locus: 20q11.23
CTCFL Gene Summary
CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
Gene Name: CCCTC-binding Factor Like
Chromosome: CHR20: 56072223 -56100154
Locus: 20q13.31
Gene Diseases
The RALGAPB CTCFL Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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