RALGAPA1-SLC25A21 Fusion FISH Probe
The RALGAPA1-SLC25A21 Fusion FISH Probe is used to confirm a fusion of the RALGAPA1 and SLC25A21 genes. The fusion of the RALGAPA1 and SLC25A21 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RALGAPA1-SLC25A21-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RALGAPA1-SLC25A21-20-RERE | 20 (40 μL) | 200 μL |
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| RALGAPA1-SLC25A21-20-REOR | 20 (40 μL) | 200 μL |
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| RALGAPA1-SLC25A21-20-REGO | 20 (40 μL) | 200 μL |
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| RALGAPA1-SLC25A21-20-REGR | 20 (40 μL) | 200 μL |
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| RALGAPA1-SLC25A21-20-REAQ | 20 (40 μL) | 200 μL |
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| RALGAPA1-SLC25A21-20-ORRE | 20 (40 μL) | 200 μL |
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| RALGAPA1-SLC25A21-20-OROR | 20 (40 μL) | 200 μL |
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| RALGAPA1-SLC25A21-20-ORGO | 20 (40 μL) | 200 μL |
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| RALGAPA1-SLC25A21-20-ORAQ | 20 (40 μL) | 200 μL |
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| RALGAPA1-SLC25A21-20-GORE | 20 (40 μL) | 200 μL |
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| RALGAPA1-SLC25A21-20-GOOR | 20 (40 μL) | 200 μL |
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| RALGAPA1-SLC25A21-20-GOGO | 20 (40 μL) | 200 μL |
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| RALGAPA1-SLC25A21-20-GOGR | 20 (40 μL) | 200 μL |
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| RALGAPA1-SLC25A21-20-GOAQ | 20 (40 μL) | 200 μL |
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| RALGAPA1-SLC25A21-20-GRRE | 20 (40 μL) | 200 μL |
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| RALGAPA1-SLC25A21-20-GROR | 20 (40 μL) | 200 μL |
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| RALGAPA1-SLC25A21-20-GRGO | 20 (40 μL) | 200 μL |
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| RALGAPA1-SLC25A21-20-GRGR | 20 (40 μL) | 200 μL |
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| RALGAPA1-SLC25A21-20-GRAQ | 20 (40 μL) | 200 μL |
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| RALGAPA1-SLC25A21-20-AQRE | 20 (40 μL) | 200 μL |
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| RALGAPA1-SLC25A21-20-AQOR | 20 (40 μL) | 200 μL |
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| RALGAPA1-SLC25A21-20-AQGO | 20 (40 μL) | 200 μL |
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| RALGAPA1-SLC25A21-20-AQGR | 20 (40 μL) | 200 μL |
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| RALGAPA1-SLC25A21-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC25A21 Gene Summary
SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.[supplied by OMIM, Apr 2004]
Gene Name: Solute Carrier Family 25 Member 21
Chromosome: CHR14: 37147125 -37641865
Locus: 14q13.3
RALGAPA1 Gene Summary
This gene encodes a major subunit of the RAL-GTPase activating protein. A similar protein in mouse binds E12, a transcriptional regulator of immunoglobulin genes. The mouse protein also functions in skeletal muscle by binding to the regulatory 14-3-3 proteins upon stimulation with insulin or muscle contraction. A pseudogene of this gene has been identified on chromosome 9. [provided by RefSeq, Oct 2016]
Gene Name: Ral GTPase Activating Protein Catalytic Alpha Subunit 1
Chromosome: CHR14: 36007557 -36278432
Locus: 14q13.2
Gene Diseases
The RALGAPA1 SLC25A21 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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