RAI2-PPP2R1B Fusion FISH Probe
The RAI2-PPP2R1B Fusion FISH Probe is used to confirm a fusion of the RAI2 and PPP2R1B genes. The fusion of the RAI2 and PPP2R1B genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RAI2-PPP2R1B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RAI2-PPP2R1B-20-RERE | 20 (40 μL) | 200 μL |
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| RAI2-PPP2R1B-20-REOR | 20 (40 μL) | 200 μL |
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| RAI2-PPP2R1B-20-REGO | 20 (40 μL) | 200 μL |
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| RAI2-PPP2R1B-20-REGR | 20 (40 μL) | 200 μL |
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| RAI2-PPP2R1B-20-REAQ | 20 (40 μL) | 200 μL |
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| RAI2-PPP2R1B-20-ORRE | 20 (40 μL) | 200 μL |
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| RAI2-PPP2R1B-20-OROR | 20 (40 μL) | 200 μL |
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| RAI2-PPP2R1B-20-ORGO | 20 (40 μL) | 200 μL |
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| RAI2-PPP2R1B-20-ORAQ | 20 (40 μL) | 200 μL |
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| RAI2-PPP2R1B-20-GORE | 20 (40 μL) | 200 μL |
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| RAI2-PPP2R1B-20-GOOR | 20 (40 μL) | 200 μL |
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| RAI2-PPP2R1B-20-GOGO | 20 (40 μL) | 200 μL |
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| RAI2-PPP2R1B-20-GOGR | 20 (40 μL) | 200 μL |
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| RAI2-PPP2R1B-20-GOAQ | 20 (40 μL) | 200 μL |
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| RAI2-PPP2R1B-20-GRRE | 20 (40 μL) | 200 μL |
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| RAI2-PPP2R1B-20-GROR | 20 (40 μL) | 200 μL |
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| RAI2-PPP2R1B-20-GRGO | 20 (40 μL) | 200 μL |
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| RAI2-PPP2R1B-20-GRGR | 20 (40 μL) | 200 μL |
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| RAI2-PPP2R1B-20-GRAQ | 20 (40 μL) | 200 μL |
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| RAI2-PPP2R1B-20-AQRE | 20 (40 μL) | 200 μL |
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| RAI2-PPP2R1B-20-AQOR | 20 (40 μL) | 200 μL |
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| RAI2-PPP2R1B-20-AQGO | 20 (40 μL) | 200 μL |
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| RAI2-PPP2R1B-20-AQGR | 20 (40 μL) | 200 μL |
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| RAI2-PPP2R1B-20-AQAQ | 20 (40 μL) | 200 μL |
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PPP2R1B Gene Summary
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]
Gene Name: Protein Phosphatase 2 Scaffold Subunit Abeta
Chromosome: CHR11: 111597631 -111637169
Locus: 11q23.1
RAI2 Gene Summary
Retinoic acid plays a critical role in development, cellular growth, and differentiation. The specific function of this retinoic acid-induced gene has not yet been determined but it may play a role in development. The chromosomal location of this gene designates it to be a candidate for diseases such as Nance-Horan syndrome, sensorineural deafness, non-specific X-linked cognitive disability, oral-facial-digital syndrome, and Fried syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Gene Name: Retinoic Acid Induced 2
Chromosome: CHRX: 17818168 -17879457
Locus: Xp22.13
Gene Diseases
The RAI2 PPP2R1B Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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