RAI14-SCP2 Fusion FISH Probe
The RAI14-SCP2 Fusion FISH Probe is used to confirm a fusion of the RAI14 and SCP2 genes. The fusion of the RAI14 and SCP2 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RAI14-SCP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RAI14-SCP2-20-RERE | 20 (40 μL) | 200 μL |
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| RAI14-SCP2-20-REOR | 20 (40 μL) | 200 μL |
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| RAI14-SCP2-20-REGO | 20 (40 μL) | 200 μL |
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| RAI14-SCP2-20-REGR | 20 (40 μL) | 200 μL |
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| RAI14-SCP2-20-REAQ | 20 (40 μL) | 200 μL |
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| RAI14-SCP2-20-ORRE | 20 (40 μL) | 200 μL |
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| RAI14-SCP2-20-OROR | 20 (40 μL) | 200 μL |
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| RAI14-SCP2-20-ORGO | 20 (40 μL) | 200 μL |
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| RAI14-SCP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| RAI14-SCP2-20-GORE | 20 (40 μL) | 200 μL |
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| RAI14-SCP2-20-GOOR | 20 (40 μL) | 200 μL |
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| RAI14-SCP2-20-GOGO | 20 (40 μL) | 200 μL |
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| RAI14-SCP2-20-GOGR | 20 (40 μL) | 200 μL |
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| RAI14-SCP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| RAI14-SCP2-20-GRRE | 20 (40 μL) | 200 μL |
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| RAI14-SCP2-20-GROR | 20 (40 μL) | 200 μL |
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| RAI14-SCP2-20-GRGO | 20 (40 μL) | 200 μL |
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| RAI14-SCP2-20-GRGR | 20 (40 μL) | 200 μL |
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| RAI14-SCP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| RAI14-SCP2-20-AQRE | 20 (40 μL) | 200 μL |
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| RAI14-SCP2-20-AQOR | 20 (40 μL) | 200 μL |
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| RAI14-SCP2-20-AQGO | 20 (40 μL) | 200 μL |
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| RAI14-SCP2-20-AQGR | 20 (40 μL) | 200 μL |
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| RAI14-SCP2-20-AQAQ | 20 (40 μL) | 200 μL |
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SCP2 Gene Summary
This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.[provided by RefSeq, Aug 2010]
Gene Name: Sterol Carrier Protein 2
Chromosome: CHR1: 53392900 -53517289
Locus: 1p32.3
RAI14 Gene Summary
The Retinoic Acid Induced 14 (RAI14) gene is located on chr5 :34656432-34832717 at 5p13.2.
Gene Name: Retinoic Acid Induced 14
Chromosome: CHR5: 34656432 -34832717
Locus: 5p13.2
Gene Diseases
The RAI14 SCP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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