RAI1-ATP5G1 Fusion FISH Probe
The RAI1-ATP5G1 Fusion FISH Probe is used to confirm a fusion of the RAI1 and ATP5G1 genes. The fusion of the RAI1 and ATP5G1 genes has been associated with Thymoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RAI1-ATP5G1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RAI1-ATP5G1-20-RERE | 20 (40 μL) | 200 μL |
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| RAI1-ATP5G1-20-REOR | 20 (40 μL) | 200 μL |
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| RAI1-ATP5G1-20-REGO | 20 (40 μL) | 200 μL |
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| RAI1-ATP5G1-20-REGR | 20 (40 μL) | 200 μL |
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| RAI1-ATP5G1-20-REAQ | 20 (40 μL) | 200 μL |
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| RAI1-ATP5G1-20-ORRE | 20 (40 μL) | 200 μL |
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| RAI1-ATP5G1-20-OROR | 20 (40 μL) | 200 μL |
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| RAI1-ATP5G1-20-ORGO | 20 (40 μL) | 200 μL |
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| RAI1-ATP5G1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RAI1-ATP5G1-20-GORE | 20 (40 μL) | 200 μL |
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| RAI1-ATP5G1-20-GOOR | 20 (40 μL) | 200 μL |
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| RAI1-ATP5G1-20-GOGO | 20 (40 μL) | 200 μL |
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| RAI1-ATP5G1-20-GOGR | 20 (40 μL) | 200 μL |
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| RAI1-ATP5G1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RAI1-ATP5G1-20-GRRE | 20 (40 μL) | 200 μL |
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| RAI1-ATP5G1-20-GROR | 20 (40 μL) | 200 μL |
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| RAI1-ATP5G1-20-GRGO | 20 (40 μL) | 200 μL |
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| RAI1-ATP5G1-20-GRGR | 20 (40 μL) | 200 μL |
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| RAI1-ATP5G1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RAI1-ATP5G1-20-AQRE | 20 (40 μL) | 200 μL |
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| RAI1-ATP5G1-20-AQOR | 20 (40 μL) | 200 μL |
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| RAI1-ATP5G1-20-AQGO | 20 (40 μL) | 200 μL |
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| RAI1-ATP5G1-20-AQGR | 20 (40 μL) | 200 μL |
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| RAI1-ATP5G1-20-AQAQ | 20 (40 μL) | 200 μL |
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ATP5G1 Gene Summary
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene is one of three genes that encode subunit c of the proton channel. Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Gene Name: ATP Synthase, H+ Transporting, Mitochondrial Fo Complex Subunit C1 (subunit 9)
Chromosome: CHR17: 46970147 -46973232
Locus: 17q21.32
RAI1 Gene Summary
This gene is located within the Smith-Magenis syndrome region on chromosome 17. It is highly similar to its mouse counterpart and is expressed at high levels mainly in neuronal tissues. The protein encoded by this gene includes a polymorphic polyglutamine tract in the N-terminal domain. Expression of the mouse counterpart in neurons is induced by retinoic acid. This gene is associated with both the severity of the phenotype and the response to medication in schizophrenic patients. [provided by RefSeq, Jul 2008]
Gene Name: Retinoic Acid Induced 1
Chromosome: CHR17: 17584786 -17714765
Locus: 17p11.2
Gene Diseases
The RAI1 ATP5G1 Fusion has been associated with the following diseases:
| Disease Name |
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| Thymoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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