RAB7A-WDR5 Fusion FISH Probe
The RAB7A-WDR5 Fusion FISH Probe is used to confirm a fusion of the RAB7A and WDR5 genes. The fusion of the RAB7A and WDR5 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RAB7A-WDR5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RAB7A-WDR5-20-RERE | 20 (40 μL) | 200 μL |
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| RAB7A-WDR5-20-REOR | 20 (40 μL) | 200 μL |
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| RAB7A-WDR5-20-REGO | 20 (40 μL) | 200 μL |
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| RAB7A-WDR5-20-REGR | 20 (40 μL) | 200 μL |
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| RAB7A-WDR5-20-REAQ | 20 (40 μL) | 200 μL |
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| RAB7A-WDR5-20-ORRE | 20 (40 μL) | 200 μL |
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| RAB7A-WDR5-20-OROR | 20 (40 μL) | 200 μL |
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| RAB7A-WDR5-20-ORGO | 20 (40 μL) | 200 μL |
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| RAB7A-WDR5-20-ORAQ | 20 (40 μL) | 200 μL |
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| RAB7A-WDR5-20-GORE | 20 (40 μL) | 200 μL |
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| RAB7A-WDR5-20-GOOR | 20 (40 μL) | 200 μL |
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| RAB7A-WDR5-20-GOGO | 20 (40 μL) | 200 μL |
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| RAB7A-WDR5-20-GOGR | 20 (40 μL) | 200 μL |
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| RAB7A-WDR5-20-GOAQ | 20 (40 μL) | 200 μL |
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| RAB7A-WDR5-20-GRRE | 20 (40 μL) | 200 μL |
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| RAB7A-WDR5-20-GROR | 20 (40 μL) | 200 μL |
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| RAB7A-WDR5-20-GRGO | 20 (40 μL) | 200 μL |
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| RAB7A-WDR5-20-GRGR | 20 (40 μL) | 200 μL |
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| RAB7A-WDR5-20-GRAQ | 20 (40 μL) | 200 μL |
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| RAB7A-WDR5-20-AQRE | 20 (40 μL) | 200 μL |
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| RAB7A-WDR5-20-AQOR | 20 (40 μL) | 200 μL |
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| RAB7A-WDR5-20-AQGO | 20 (40 μL) | 200 μL |
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| RAB7A-WDR5-20-AQGR | 20 (40 μL) | 200 μL |
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| RAB7A-WDR5-20-AQAQ | 20 (40 μL) | 200 μL |
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RAB7A Gene Summary
RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq, Jul 2008]
Gene Name: RAB7A, Member RAS Oncogene Family
Chromosome: CHR3: 128444978 -128533641
Locus: 3q21.3
WDR5 Gene Summary
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Gene Name: WD Repeat Domain 5
Chromosome: CHR9: 137001209 -137025094
Locus: 9q34.2
Gene Diseases
The RAB7A WDR5 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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