RAB6A-TUT1 Fusion FISH Probe
The RAB6A-TUT1 Fusion FISH Probe is used to confirm a fusion of the RAB6A and TUT1 genes. The fusion of the RAB6A and TUT1 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RAB6A-TUT1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RAB6A-TUT1-20-RERE | 20 (40 μL) | 200 μL |
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| RAB6A-TUT1-20-REOR | 20 (40 μL) | 200 μL |
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| RAB6A-TUT1-20-REGO | 20 (40 μL) | 200 μL |
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| RAB6A-TUT1-20-REGR | 20 (40 μL) | 200 μL |
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| RAB6A-TUT1-20-REAQ | 20 (40 μL) | 200 μL |
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| RAB6A-TUT1-20-ORRE | 20 (40 μL) | 200 μL |
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| RAB6A-TUT1-20-OROR | 20 (40 μL) | 200 μL |
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| RAB6A-TUT1-20-ORGO | 20 (40 μL) | 200 μL |
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| RAB6A-TUT1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RAB6A-TUT1-20-GORE | 20 (40 μL) | 200 μL |
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| RAB6A-TUT1-20-GOOR | 20 (40 μL) | 200 μL |
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| RAB6A-TUT1-20-GOGO | 20 (40 μL) | 200 μL |
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| RAB6A-TUT1-20-GOGR | 20 (40 μL) | 200 μL |
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| RAB6A-TUT1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RAB6A-TUT1-20-GRRE | 20 (40 μL) | 200 μL |
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| RAB6A-TUT1-20-GROR | 20 (40 μL) | 200 μL |
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| RAB6A-TUT1-20-GRGO | 20 (40 μL) | 200 μL |
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| RAB6A-TUT1-20-GRGR | 20 (40 μL) | 200 μL |
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| RAB6A-TUT1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RAB6A-TUT1-20-AQRE | 20 (40 μL) | 200 μL |
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| RAB6A-TUT1-20-AQOR | 20 (40 μL) | 200 μL |
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| RAB6A-TUT1-20-AQGO | 20 (40 μL) | 200 μL |
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| RAB6A-TUT1-20-AQGR | 20 (40 μL) | 200 μL |
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| RAB6A-TUT1-20-AQAQ | 20 (40 μL) | 200 μL |
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RAB6A Gene Summary
This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Gene Name: RAB6A, Member RAS Oncogene Family
Chromosome: CHR11: 73386682 -73472201
Locus: 11q13.4
TUT1 Gene Summary
This gene encodes a nucleotidyl transferase that functions as both a terminal uridylyltransferase and a nuclear poly(A) polymerase. The encoded enzyme specifically adds and removes nucleotides from the 3' end of small nuclear RNAs and select mRNAs and may function in controlling gene expression and cell proliferation.[provided by RefSeq, Apr 2009]
Gene Name: Terminal Uridylyl Transferase 1, U6 SnRNA-specific
Chromosome: CHR11: 62342516 -62359109
Locus: 11q12.3
Gene Diseases
The RAB6A TUT1 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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