RAB5B-DGKA Fusion FISH Probe
The RAB5B-DGKA Fusion FISH Probe is used to confirm a fusion of the RAB5B and DGKA genes. The fusion of the RAB5B and DGKA genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RAB5B-DGKA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RAB5B-DGKA-20-RERE | 20 (40 μL) | 200 μL |
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| RAB5B-DGKA-20-REOR | 20 (40 μL) | 200 μL |
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| RAB5B-DGKA-20-REGO | 20 (40 μL) | 200 μL |
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| RAB5B-DGKA-20-REGR | 20 (40 μL) | 200 μL |
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| RAB5B-DGKA-20-REAQ | 20 (40 μL) | 200 μL |
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| RAB5B-DGKA-20-ORRE | 20 (40 μL) | 200 μL |
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| RAB5B-DGKA-20-OROR | 20 (40 μL) | 200 μL |
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| RAB5B-DGKA-20-ORGO | 20 (40 μL) | 200 μL |
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| RAB5B-DGKA-20-ORAQ | 20 (40 μL) | 200 μL |
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| RAB5B-DGKA-20-GORE | 20 (40 μL) | 200 μL |
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| RAB5B-DGKA-20-GOOR | 20 (40 μL) | 200 μL |
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| RAB5B-DGKA-20-GOGO | 20 (40 μL) | 200 μL |
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| RAB5B-DGKA-20-GOGR | 20 (40 μL) | 200 μL |
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| RAB5B-DGKA-20-GOAQ | 20 (40 μL) | 200 μL |
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| RAB5B-DGKA-20-GRRE | 20 (40 μL) | 200 μL |
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| RAB5B-DGKA-20-GROR | 20 (40 μL) | 200 μL |
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| RAB5B-DGKA-20-GRGO | 20 (40 μL) | 200 μL |
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| RAB5B-DGKA-20-GRGR | 20 (40 μL) | 200 μL |
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| RAB5B-DGKA-20-GRAQ | 20 (40 μL) | 200 μL |
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| RAB5B-DGKA-20-AQRE | 20 (40 μL) | 200 μL |
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| RAB5B-DGKA-20-AQOR | 20 (40 μL) | 200 μL |
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| RAB5B-DGKA-20-AQGO | 20 (40 μL) | 200 μL |
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| RAB5B-DGKA-20-AQGR | 20 (40 μL) | 200 μL |
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| RAB5B-DGKA-20-AQAQ | 20 (40 μL) | 200 μL |
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DGKA Gene Summary
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Several transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Apr 2017]
Gene Name: Diacylglycerol Kinase Alpha
Chromosome: CHR12: 56324945 -56347807
Locus: 12q13.2
RAB5B Gene Summary
The RAB5B, Member RAS Oncogene Family (RAB5B) gene is located on chr12 :56367861-56388488 at 12q13.2.
Gene Name: RAB5B, Member RAS Oncogene Family
Chromosome: CHR12: 56367861 -56388488
Locus: 12q13.2
Gene Diseases
The RAB5B DGKA Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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