RAB4B-EXOC4 Fusion FISH Probe
The RAB4B-EXOC4 Fusion FISH Probe is used to confirm a fusion of the RAB4B and EXOC4 genes. The fusion of the RAB4B and EXOC4 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RAB4B-EXOC4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RAB4B-EXOC4-20-RERE | 20 (40 μL) | 200 μL |
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| RAB4B-EXOC4-20-REOR | 20 (40 μL) | 200 μL |
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| RAB4B-EXOC4-20-REGO | 20 (40 μL) | 200 μL |
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| RAB4B-EXOC4-20-REGR | 20 (40 μL) | 200 μL |
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| RAB4B-EXOC4-20-REAQ | 20 (40 μL) | 200 μL |
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| RAB4B-EXOC4-20-ORRE | 20 (40 μL) | 200 μL |
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| RAB4B-EXOC4-20-OROR | 20 (40 μL) | 200 μL |
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| RAB4B-EXOC4-20-ORGO | 20 (40 μL) | 200 μL |
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| RAB4B-EXOC4-20-ORAQ | 20 (40 μL) | 200 μL |
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| RAB4B-EXOC4-20-GORE | 20 (40 μL) | 200 μL |
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| RAB4B-EXOC4-20-GOOR | 20 (40 μL) | 200 μL |
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| RAB4B-EXOC4-20-GOGO | 20 (40 μL) | 200 μL |
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| RAB4B-EXOC4-20-GOGR | 20 (40 μL) | 200 μL |
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| RAB4B-EXOC4-20-GOAQ | 20 (40 μL) | 200 μL |
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| RAB4B-EXOC4-20-GRRE | 20 (40 μL) | 200 μL |
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| RAB4B-EXOC4-20-GROR | 20 (40 μL) | 200 μL |
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| RAB4B-EXOC4-20-GRGO | 20 (40 μL) | 200 μL |
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| RAB4B-EXOC4-20-GRGR | 20 (40 μL) | 200 μL |
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| RAB4B-EXOC4-20-GRAQ | 20 (40 μL) | 200 μL |
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| RAB4B-EXOC4-20-AQRE | 20 (40 μL) | 200 μL |
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| RAB4B-EXOC4-20-AQOR | 20 (40 μL) | 200 μL |
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| RAB4B-EXOC4-20-AQGO | 20 (40 μL) | 200 μL |
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| RAB4B-EXOC4-20-AQGR | 20 (40 μL) | 200 μL |
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| RAB4B-EXOC4-20-AQAQ | 20 (40 μL) | 200 μL |
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RAB4B Gene Summary
RAB proteins, such as RAB4B, are members of the RAS superfamily of small GTPases that are involved in vesicular trafficking (He et al., 2002 [PubMed 12450215]).[supplied by OMIM, Aug 2009]
Gene Name: RAB4B, Member RAS Oncogene Family
Chromosome: CHR19: 41284123 -41302849
Locus: 19q13.2
EXOC4 Gene Summary
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: Exocyst Complex Component 4
Chromosome: CHR7: 132937822 -133750513
Locus: 7q33
Gene Diseases
The RAB4B EXOC4 Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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