RAB33B-NAA15 Fusion FISH Probe
The RAB33B-NAA15 Fusion FISH Probe is used to confirm a fusion of the RAB33B and NAA15 genes. The fusion of the RAB33B and NAA15 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RAB33B-NAA15-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RAB33B-NAA15-20-RERE | 20 (40 μL) | 200 μL |
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| RAB33B-NAA15-20-REOR | 20 (40 μL) | 200 μL |
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| RAB33B-NAA15-20-REGO | 20 (40 μL) | 200 μL |
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| RAB33B-NAA15-20-REGR | 20 (40 μL) | 200 μL |
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| RAB33B-NAA15-20-REAQ | 20 (40 μL) | 200 μL |
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| RAB33B-NAA15-20-ORRE | 20 (40 μL) | 200 μL |
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| RAB33B-NAA15-20-OROR | 20 (40 μL) | 200 μL |
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| RAB33B-NAA15-20-ORGO | 20 (40 μL) | 200 μL |
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| RAB33B-NAA15-20-ORAQ | 20 (40 μL) | 200 μL |
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| RAB33B-NAA15-20-GORE | 20 (40 μL) | 200 μL |
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| RAB33B-NAA15-20-GOOR | 20 (40 μL) | 200 μL |
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| RAB33B-NAA15-20-GOGO | 20 (40 μL) | 200 μL |
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| RAB33B-NAA15-20-GOGR | 20 (40 μL) | 200 μL |
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| RAB33B-NAA15-20-GOAQ | 20 (40 μL) | 200 μL |
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| RAB33B-NAA15-20-GRRE | 20 (40 μL) | 200 μL |
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| RAB33B-NAA15-20-GROR | 20 (40 μL) | 200 μL |
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| RAB33B-NAA15-20-GRGO | 20 (40 μL) | 200 μL |
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| RAB33B-NAA15-20-GRGR | 20 (40 μL) | 200 μL |
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| RAB33B-NAA15-20-GRAQ | 20 (40 μL) | 200 μL |
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| RAB33B-NAA15-20-AQRE | 20 (40 μL) | 200 μL |
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| RAB33B-NAA15-20-AQOR | 20 (40 μL) | 200 μL |
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| RAB33B-NAA15-20-AQGO | 20 (40 μL) | 200 μL |
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| RAB33B-NAA15-20-AQGR | 20 (40 μL) | 200 μL |
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| RAB33B-NAA15-20-AQAQ | 20 (40 μL) | 200 μL |
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NAA15 Gene Summary
N-alpha-acetylation is among the most common post-translational protein modifications in eukaryotic cells. This process involves the transfer of an acetyl group from acetyl-coenzyme A to the alpha-amino group on a nascent polypeptide and is essential for normal cell function. This gene encodes the auxillary subunit of the N-terminal acetyltransferase A (NatA) complex. [provided by RefSeq, Jan 2017]
Gene Name: N(alpha)-acetyltransferase 15, NatA Auxiliary Subunit
Chromosome: CHR4: 140222675 -140311935
Locus: 4q31.1
RAB33B Gene Summary
This gene encodes a small GTP-binding protein of the Rab GTPase family, whose members function in vesicle transport during protein secretion and endocytosis. Rab GTPases are active, membrane-associated proteins that recruit effector proteins in the GTP-bound state and inactive cytosolic proteins when in a GDP-bound state. The protein encoded by this gene is ubiquitously expressed and has been implicated in Golgi to endoplasmic reticulum cycling of Golgi enzymes. In addition, this protein regulates Golgi homeostasis and coordinates intra-Golgi retrograde trafficking. Allelic variants in this gene have been associated with Dyggve-Melchior-Clausen syndrome and Smith-McCort dysplasia 2, which are autosomal recessive spondyloepimetaphyseal dysplasias characterized by skeletal abnormalities. [provided by RefSeq, Sep 2016]
Gene Name: RAB33B, Member RAS Oncogene Family
Chromosome: CHR4: 140374960 -140397069
Locus: 4q31.1
Gene Diseases
The RAB33B NAA15 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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