RAB1B-MTMR2 Fusion FISH Probe
The RAB1B-MTMR2 Fusion FISH Probe is used to confirm a fusion of the RAB1B and MTMR2 genes. The fusion of the RAB1B and MTMR2 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RAB1B-MTMR2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| RAB1B-MTMR2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| RAB1B-MTMR2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| RAB1B-MTMR2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| RAB1B-MTMR2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| RAB1B-MTMR2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| RAB1B-MTMR2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| RAB1B-MTMR2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| RAB1B-MTMR2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| RAB1B-MTMR2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| RAB1B-MTMR2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| RAB1B-MTMR2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| RAB1B-MTMR2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| RAB1B-MTMR2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| RAB1B-MTMR2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| RAB1B-MTMR2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| RAB1B-MTMR2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| RAB1B-MTMR2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| RAB1B-MTMR2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| RAB1B-MTMR2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| RAB1B-MTMR2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| RAB1B-MTMR2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| RAB1B-MTMR2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| RAB1B-MTMR2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| RAB1B-MTMR2-20-AQAQ | 20 (40 μL) | 200 μL |
|
MTMR2 Gene Summary
This gene is a member of the myotubularin family of phosphoinositide lipid phosphatases. The encoded protein possesses phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Gene Name: Myotubularin Related Protein 2
Chromosome: CHR11: 95566043 -95657371
Locus: 11q21
RAB1B Gene Summary
Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi (Chen et al., 1997 [PubMed 9030196]; Alvarez et al., 2003 [PubMed 12802079]).[supplied by OMIM, Jan 2009]
Gene Name: RAB1B, Member RAS Oncogene Family
Chromosome: CHR11: 66036055 -66044963
Locus: 11q13.2
Gene Diseases
The RAB1B MTMR2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|