RAB11FIP3-RGS11 Fusion FISH Probe
The RAB11FIP3-RGS11 Fusion FISH Probe is used to confirm a fusion of the RAB11FIP3 and RGS11 genes. The fusion of the RAB11FIP3 and RGS11 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RAB11FIP3-RGS11-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RAB11FIP3-RGS11-20-RERE | 20 (40 μL) | 200 μL |
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| RAB11FIP3-RGS11-20-REOR | 20 (40 μL) | 200 μL |
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| RAB11FIP3-RGS11-20-REGO | 20 (40 μL) | 200 μL |
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| RAB11FIP3-RGS11-20-REGR | 20 (40 μL) | 200 μL |
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| RAB11FIP3-RGS11-20-REAQ | 20 (40 μL) | 200 μL |
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| RAB11FIP3-RGS11-20-ORRE | 20 (40 μL) | 200 μL |
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| RAB11FIP3-RGS11-20-OROR | 20 (40 μL) | 200 μL |
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| RAB11FIP3-RGS11-20-ORGO | 20 (40 μL) | 200 μL |
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| RAB11FIP3-RGS11-20-ORAQ | 20 (40 μL) | 200 μL |
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| RAB11FIP3-RGS11-20-GORE | 20 (40 μL) | 200 μL |
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| RAB11FIP3-RGS11-20-GOOR | 20 (40 μL) | 200 μL |
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| RAB11FIP3-RGS11-20-GOGO | 20 (40 μL) | 200 μL |
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| RAB11FIP3-RGS11-20-GOGR | 20 (40 μL) | 200 μL |
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| RAB11FIP3-RGS11-20-GOAQ | 20 (40 μL) | 200 μL |
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| RAB11FIP3-RGS11-20-GRRE | 20 (40 μL) | 200 μL |
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| RAB11FIP3-RGS11-20-GROR | 20 (40 μL) | 200 μL |
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| RAB11FIP3-RGS11-20-GRGO | 20 (40 μL) | 200 μL |
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| RAB11FIP3-RGS11-20-GRGR | 20 (40 μL) | 200 μL |
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| RAB11FIP3-RGS11-20-GRAQ | 20 (40 μL) | 200 μL |
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| RAB11FIP3-RGS11-20-AQRE | 20 (40 μL) | 200 μL |
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| RAB11FIP3-RGS11-20-AQOR | 20 (40 μL) | 200 μL |
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| RAB11FIP3-RGS11-20-AQGO | 20 (40 μL) | 200 μL |
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| RAB11FIP3-RGS11-20-AQGR | 20 (40 μL) | 200 μL |
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| RAB11FIP3-RGS11-20-AQAQ | 20 (40 μL) | 200 μL |
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RGS11 Gene Summary
The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2013]
Gene Name: Regulator Of G Protein Signaling 11
Chromosome: CHR16: 318309 -325914
Locus: 16p13.3
RAB11FIP3 Gene Summary
Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP3 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 [PubMed 11495908]).[supplied by OMIM, Mar 2008]
Gene Name: RAB11 Family Interacting Protein 3
Chromosome: CHR16: 475667 -572481
Locus: 16p13.3
Gene Diseases
The RAB11FIP3 RGS11 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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