R3HDM2-GLI1 Fusion FISH Probe
The R3HDM2-GLI1 Fusion FISH Probe is used to confirm a fusion of the R3HDM2 and GLI1 genes. The fusion of the R3HDM2 and GLI1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| R3HDM2-GLI1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| R3HDM2-GLI1-20-RERE | 20 (40 μL) | 200 μL |
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| R3HDM2-GLI1-20-REOR | 20 (40 μL) | 200 μL |
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| R3HDM2-GLI1-20-REGO | 20 (40 μL) | 200 μL |
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| R3HDM2-GLI1-20-REGR | 20 (40 μL) | 200 μL |
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| R3HDM2-GLI1-20-REAQ | 20 (40 μL) | 200 μL |
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| R3HDM2-GLI1-20-ORRE | 20 (40 μL) | 200 μL |
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| R3HDM2-GLI1-20-OROR | 20 (40 μL) | 200 μL |
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| R3HDM2-GLI1-20-ORGO | 20 (40 μL) | 200 μL |
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| R3HDM2-GLI1-20-ORAQ | 20 (40 μL) | 200 μL |
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| R3HDM2-GLI1-20-GORE | 20 (40 μL) | 200 μL |
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| R3HDM2-GLI1-20-GOOR | 20 (40 μL) | 200 μL |
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| R3HDM2-GLI1-20-GOGO | 20 (40 μL) | 200 μL |
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| R3HDM2-GLI1-20-GOGR | 20 (40 μL) | 200 μL |
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| R3HDM2-GLI1-20-GOAQ | 20 (40 μL) | 200 μL |
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| R3HDM2-GLI1-20-GRRE | 20 (40 μL) | 200 μL |
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| R3HDM2-GLI1-20-GROR | 20 (40 μL) | 200 μL |
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| R3HDM2-GLI1-20-GRGO | 20 (40 μL) | 200 μL |
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| R3HDM2-GLI1-20-GRGR | 20 (40 μL) | 200 μL |
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| R3HDM2-GLI1-20-GRAQ | 20 (40 μL) | 200 μL |
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| R3HDM2-GLI1-20-AQRE | 20 (40 μL) | 200 μL |
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| R3HDM2-GLI1-20-AQOR | 20 (40 μL) | 200 μL |
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| R3HDM2-GLI1-20-AQGO | 20 (40 μL) | 200 μL |
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| R3HDM2-GLI1-20-AQGR | 20 (40 μL) | 200 μL |
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| R3HDM2-GLI1-20-AQAQ | 20 (40 μL) | 200 μL |
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GLI1 Gene Summary
This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Gene Name: GLI Family Zinc Finger 1
Chromosome: CHR12: 57853917 -57866047
Locus: 12q13.3
R3HDM2 Gene Summary
The R3H Domain Containing 2 (R3HDM2) gene is located on chr12 :57647547-57704246 at 12q13.3.
Gene Name: R3H Domain Containing 2
Chromosome: CHR12: 57647547 -57704246
Locus: 12q13.3
Gene Diseases
The R3HDM2 GLI1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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