PYGO1-FBN1 Fusion FISH Probe
The PYGO1-FBN1 Fusion FISH Probe is used to confirm a fusion of the PYGO1 and FBN1 genes. The fusion of the PYGO1 and FBN1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PYGO1-FBN1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PYGO1-FBN1-20-RERE | 20 (40 μL) | 200 μL |
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| PYGO1-FBN1-20-REOR | 20 (40 μL) | 200 μL |
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| PYGO1-FBN1-20-REGO | 20 (40 μL) | 200 μL |
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| PYGO1-FBN1-20-REGR | 20 (40 μL) | 200 μL |
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| PYGO1-FBN1-20-REAQ | 20 (40 μL) | 200 μL |
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| PYGO1-FBN1-20-ORRE | 20 (40 μL) | 200 μL |
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| PYGO1-FBN1-20-OROR | 20 (40 μL) | 200 μL |
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| PYGO1-FBN1-20-ORGO | 20 (40 μL) | 200 μL |
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| PYGO1-FBN1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PYGO1-FBN1-20-GORE | 20 (40 μL) | 200 μL |
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| PYGO1-FBN1-20-GOOR | 20 (40 μL) | 200 μL |
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| PYGO1-FBN1-20-GOGO | 20 (40 μL) | 200 μL |
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| PYGO1-FBN1-20-GOGR | 20 (40 μL) | 200 μL |
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| PYGO1-FBN1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PYGO1-FBN1-20-GRRE | 20 (40 μL) | 200 μL |
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| PYGO1-FBN1-20-GROR | 20 (40 μL) | 200 μL |
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| PYGO1-FBN1-20-GRGO | 20 (40 μL) | 200 μL |
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| PYGO1-FBN1-20-GRGR | 20 (40 μL) | 200 μL |
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| PYGO1-FBN1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PYGO1-FBN1-20-AQRE | 20 (40 μL) | 200 μL |
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| PYGO1-FBN1-20-AQOR | 20 (40 μL) | 200 μL |
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| PYGO1-FBN1-20-AQGO | 20 (40 μL) | 200 μL |
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| PYGO1-FBN1-20-AQGR | 20 (40 μL) | 200 μL |
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| PYGO1-FBN1-20-AQAQ | 20 (40 μL) | 200 μL |
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FBN1 Gene Summary
This gene encodes a member of the fibrillin family of proteins. The encoded preproprotein is proteolytically processed to generate two proteins including the extracellular matrix component fibrillin-1 and the protein hormone asprosin. Fibrillin-1 is an extracellular matrix glycoprotein that serves as a structural component of calcium-binding microfibrils. These microfibrils provide force-bearing structural support in elastic and nonelastic connective tissue throughout the body. Asprosin, secreted by white adipose tissue, has been shown to regulate glucose homeostasis. Mutations in this gene are associated with Marfan syndrome and the related MASS phenotype, as well as ectopia lentis syndrome, Weill-Marchesani syndrome, Shprintzen-Goldberg syndrome and neonatal progeroid syndrome. [provided by RefSeq, Apr 2016]
Gene Name: Fibrillin 1
Chromosome: CHR15: 48700502 -48937985
Locus: 15q21.1
PYGO1 Gene Summary
The Pygopus Family PHD Finger 1 (PYGO1) gene is located on chr15 :55838220-55881050 at 15q21.3.
Gene Name: Pygopus Family PHD Finger 1
Chromosome: CHR15: 55838220 -55881050
Locus: 15q21.3
Gene Diseases
The PYGO1 FBN1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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