PXK-RPP14 Fusion FISH Probe
The PXK-RPP14 Fusion FISH Probe is used to confirm a fusion of the PXK and RPP14 genes. The fusion of the PXK and RPP14 genes has been associated with Ovarian Serous Cystadenocarcinoma, and Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PXK-RPP14-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PXK-RPP14-20-RERE | 20 (40 μL) | 200 μL |
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| PXK-RPP14-20-REOR | 20 (40 μL) | 200 μL |
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| PXK-RPP14-20-REGO | 20 (40 μL) | 200 μL |
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| PXK-RPP14-20-REGR | 20 (40 μL) | 200 μL |
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| PXK-RPP14-20-REAQ | 20 (40 μL) | 200 μL |
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| PXK-RPP14-20-ORRE | 20 (40 μL) | 200 μL |
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| PXK-RPP14-20-OROR | 20 (40 μL) | 200 μL |
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| PXK-RPP14-20-ORGO | 20 (40 μL) | 200 μL |
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| PXK-RPP14-20-ORAQ | 20 (40 μL) | 200 μL |
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| PXK-RPP14-20-GORE | 20 (40 μL) | 200 μL |
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| PXK-RPP14-20-GOOR | 20 (40 μL) | 200 μL |
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| PXK-RPP14-20-GOGO | 20 (40 μL) | 200 μL |
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| PXK-RPP14-20-GOGR | 20 (40 μL) | 200 μL |
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| PXK-RPP14-20-GOAQ | 20 (40 μL) | 200 μL |
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| PXK-RPP14-20-GRRE | 20 (40 μL) | 200 μL |
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| PXK-RPP14-20-GROR | 20 (40 μL) | 200 μL |
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| PXK-RPP14-20-GRGO | 20 (40 μL) | 200 μL |
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| PXK-RPP14-20-GRGR | 20 (40 μL) | 200 μL |
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| PXK-RPP14-20-GRAQ | 20 (40 μL) | 200 μL |
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| PXK-RPP14-20-AQRE | 20 (40 μL) | 200 μL |
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| PXK-RPP14-20-AQOR | 20 (40 μL) | 200 μL |
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| PXK-RPP14-20-AQGO | 20 (40 μL) | 200 μL |
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| PXK-RPP14-20-AQGR | 20 (40 μL) | 200 μL |
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| PXK-RPP14-20-AQAQ | 20 (40 μL) | 200 μL |
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RPP14 Gene Summary
This gene encodes a subunit of ribonuclease P and has 3' to 5' exoribonuclease activity. Transcripts for this gene are bicistronic and include a conserved downstream open reading frame for the hydroxyacyl-thioester dehydratase type 2 (HTD2) gene. [provided by RefSeq, May 2017]
Gene Name: Ribonuclease P/MRP Subunit P14
Chromosome: CHR3: 58291971 -58305920
Locus: 3p14.3
PXK Gene Summary
This gene encodes a phox (PX) domain-containing protein which may be involved in synaptic transmission and the ligand-induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Gene Name: PX Domain Containing Serine/threonine Kinase Like
Chromosome: CHR3: 58318616 -58410878
Locus: 3p14.3
Gene Diseases
The PXK RPP14 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
| Adrenocortical Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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