PXDNL-USP8 Fusion FISH Probe
The PXDNL-USP8 Fusion FISH Probe is used to confirm a fusion of the PXDNL and USP8 genes. The fusion of the PXDNL and USP8 genes has been associated with Skin Cutaneous Melanoma, and Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PXDNL-USP8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PXDNL-USP8-20-RERE | 20 (40 μL) | 200 μL |
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| PXDNL-USP8-20-REOR | 20 (40 μL) | 200 μL |
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| PXDNL-USP8-20-REGO | 20 (40 μL) | 200 μL |
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| PXDNL-USP8-20-REGR | 20 (40 μL) | 200 μL |
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| PXDNL-USP8-20-REAQ | 20 (40 μL) | 200 μL |
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| PXDNL-USP8-20-ORRE | 20 (40 μL) | 200 μL |
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| PXDNL-USP8-20-OROR | 20 (40 μL) | 200 μL |
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| PXDNL-USP8-20-ORGO | 20 (40 μL) | 200 μL |
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| PXDNL-USP8-20-ORAQ | 20 (40 μL) | 200 μL |
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| PXDNL-USP8-20-GORE | 20 (40 μL) | 200 μL |
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| PXDNL-USP8-20-GOOR | 20 (40 μL) | 200 μL |
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| PXDNL-USP8-20-GOGO | 20 (40 μL) | 200 μL |
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| PXDNL-USP8-20-GOGR | 20 (40 μL) | 200 μL |
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| PXDNL-USP8-20-GOAQ | 20 (40 μL) | 200 μL |
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| PXDNL-USP8-20-GRRE | 20 (40 μL) | 200 μL |
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| PXDNL-USP8-20-GROR | 20 (40 μL) | 200 μL |
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| PXDNL-USP8-20-GRGO | 20 (40 μL) | 200 μL |
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| PXDNL-USP8-20-GRGR | 20 (40 μL) | 200 μL |
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| PXDNL-USP8-20-GRAQ | 20 (40 μL) | 200 μL |
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| PXDNL-USP8-20-AQRE | 20 (40 μL) | 200 μL |
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| PXDNL-USP8-20-AQOR | 20 (40 μL) | 200 μL |
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| PXDNL-USP8-20-AQGO | 20 (40 μL) | 200 μL |
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| PXDNL-USP8-20-AQGR | 20 (40 μL) | 200 μL |
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| PXDNL-USP8-20-AQAQ | 20 (40 μL) | 200 μL |
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USP8 Gene Summary
This gene encodes a protein that belongs to the ubiquitin-specific processing protease family of proteins. The encoded protein is thought to regulate the morphology of the endosome by ubiquitination of proteins on this organelle and is involved in cargo sorting and membrane trafficking at the early endosome stage. This protein is required for the cell to enter the S phase of the cell cycle and also functions as a positive regulator in the Hedgehog signaling pathway in development. Pseudogenes of this gene are present on chromosomes 2 and 6. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Name: Ubiquitin Specific Peptidase 8
Chromosome: CHR15: 50716578 -50793277
Locus: 15q21.2
PXDNL Gene Summary
The Peroxidasin Like (PXDNL) gene is located on chr8 :52232136-52722005 at 8q11.22-q11.23.
Gene Name: Peroxidasin Like
Chromosome: CHR8: 52232136 -52722005
Locus: 8q11.22-q11.23
Gene Diseases
The PXDNL USP8 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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