PVRL2-CCL21 Fusion FISH Probe
The PVRL2-CCL21 Fusion FISH Probe is used to confirm a fusion of the PVRL2 and CCL21 genes. The fusion of the PVRL2 and CCL21 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PVRL2-CCL21-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PVRL2-CCL21-20-RERE | 20 (40 μL) | 200 μL |
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| PVRL2-CCL21-20-REOR | 20 (40 μL) | 200 μL |
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| PVRL2-CCL21-20-REGO | 20 (40 μL) | 200 μL |
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| PVRL2-CCL21-20-REGR | 20 (40 μL) | 200 μL |
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| PVRL2-CCL21-20-REAQ | 20 (40 μL) | 200 μL |
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| PVRL2-CCL21-20-ORRE | 20 (40 μL) | 200 μL |
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| PVRL2-CCL21-20-OROR | 20 (40 μL) | 200 μL |
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| PVRL2-CCL21-20-ORGO | 20 (40 μL) | 200 μL |
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| PVRL2-CCL21-20-ORAQ | 20 (40 μL) | 200 μL |
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| PVRL2-CCL21-20-GORE | 20 (40 μL) | 200 μL |
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| PVRL2-CCL21-20-GOOR | 20 (40 μL) | 200 μL |
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| PVRL2-CCL21-20-GOGO | 20 (40 μL) | 200 μL |
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| PVRL2-CCL21-20-GOGR | 20 (40 μL) | 200 μL |
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| PVRL2-CCL21-20-GOAQ | 20 (40 μL) | 200 μL |
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| PVRL2-CCL21-20-GRRE | 20 (40 μL) | 200 μL |
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| PVRL2-CCL21-20-GROR | 20 (40 μL) | 200 μL |
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| PVRL2-CCL21-20-GRGO | 20 (40 μL) | 200 μL |
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| PVRL2-CCL21-20-GRGR | 20 (40 μL) | 200 μL |
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| PVRL2-CCL21-20-GRAQ | 20 (40 μL) | 200 μL |
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| PVRL2-CCL21-20-AQRE | 20 (40 μL) | 200 μL |
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| PVRL2-CCL21-20-AQOR | 20 (40 μL) | 200 μL |
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| PVRL2-CCL21-20-AQGO | 20 (40 μL) | 200 μL |
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| PVRL2-CCL21-20-AQGR | 20 (40 μL) | 200 μL |
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| PVRL2-CCL21-20-AQAQ | 20 (40 μL) | 200 μL |
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CCL21 Gene Summary
This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). [provided by RefSeq, Sep 2014]
Gene Name: C-C Motif Chemokine Ligand 21
Chromosome: CHR9: 34709001 -34710147
Locus: 9p13.3
Gene Diseases
The PVRL2 CCL21 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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