PUSL1-AGRN Fusion FISH Probe
The PUSL1-AGRN Fusion FISH Probe is used to confirm a fusion of the PUSL1 and AGRN genes. The fusion of the PUSL1 and AGRN genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PUSL1-AGRN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PUSL1-AGRN-20-RERE | 20 (40 μL) | 200 μL |
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| PUSL1-AGRN-20-REOR | 20 (40 μL) | 200 μL |
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| PUSL1-AGRN-20-REGO | 20 (40 μL) | 200 μL |
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| PUSL1-AGRN-20-REGR | 20 (40 μL) | 200 μL |
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| PUSL1-AGRN-20-REAQ | 20 (40 μL) | 200 μL |
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| PUSL1-AGRN-20-ORRE | 20 (40 μL) | 200 μL |
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| PUSL1-AGRN-20-OROR | 20 (40 μL) | 200 μL |
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| PUSL1-AGRN-20-ORGO | 20 (40 μL) | 200 μL |
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| PUSL1-AGRN-20-ORAQ | 20 (40 μL) | 200 μL |
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| PUSL1-AGRN-20-GORE | 20 (40 μL) | 200 μL |
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| PUSL1-AGRN-20-GOOR | 20 (40 μL) | 200 μL |
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| PUSL1-AGRN-20-GOGO | 20 (40 μL) | 200 μL |
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| PUSL1-AGRN-20-GOGR | 20 (40 μL) | 200 μL |
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| PUSL1-AGRN-20-GOAQ | 20 (40 μL) | 200 μL |
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| PUSL1-AGRN-20-GRRE | 20 (40 μL) | 200 μL |
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| PUSL1-AGRN-20-GROR | 20 (40 μL) | 200 μL |
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| PUSL1-AGRN-20-GRGO | 20 (40 μL) | 200 μL |
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| PUSL1-AGRN-20-GRGR | 20 (40 μL) | 200 μL |
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| PUSL1-AGRN-20-GRAQ | 20 (40 μL) | 200 μL |
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| PUSL1-AGRN-20-AQRE | 20 (40 μL) | 200 μL |
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| PUSL1-AGRN-20-AQOR | 20 (40 μL) | 200 μL |
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| PUSL1-AGRN-20-AQGO | 20 (40 μL) | 200 μL |
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| PUSL1-AGRN-20-AQGR | 20 (40 μL) | 200 μL |
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| PUSL1-AGRN-20-AQAQ | 20 (40 μL) | 200 μL |
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PUSL1 Gene Summary
The Pseudouridylate Synthase-like 1 (PUSL1) gene is located on chr1 :1243993-1247057 at 1p36.33.
Gene Name: Pseudouridylate Synthase-like 1
Chromosome: CHR1: 1243993 -1247057
Locus: 1p36.33
AGRN Gene Summary
This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015]
Gene Name: Agrin
Chromosome: CHR1: 955502 -991499
Locus: 1p36.33
Gene Diseases
The PUSL1 AGRN Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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