PUS1-CTNNBIP1 Fusion FISH Probe
The PUS1-CTNNBIP1 Fusion FISH Probe is used to confirm a fusion of the PUS1 and CTNNBIP1 genes. The fusion of the PUS1 and CTNNBIP1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PUS1-CTNNBIP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PUS1-CTNNBIP1-20-RERE | 20 (40 μL) | 200 μL |
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| PUS1-CTNNBIP1-20-REOR | 20 (40 μL) | 200 μL |
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| PUS1-CTNNBIP1-20-REGO | 20 (40 μL) | 200 μL |
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| PUS1-CTNNBIP1-20-REGR | 20 (40 μL) | 200 μL |
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| PUS1-CTNNBIP1-20-REAQ | 20 (40 μL) | 200 μL |
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| PUS1-CTNNBIP1-20-ORRE | 20 (40 μL) | 200 μL |
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| PUS1-CTNNBIP1-20-OROR | 20 (40 μL) | 200 μL |
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| PUS1-CTNNBIP1-20-ORGO | 20 (40 μL) | 200 μL |
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| PUS1-CTNNBIP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PUS1-CTNNBIP1-20-GORE | 20 (40 μL) | 200 μL |
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| PUS1-CTNNBIP1-20-GOOR | 20 (40 μL) | 200 μL |
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| PUS1-CTNNBIP1-20-GOGO | 20 (40 μL) | 200 μL |
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| PUS1-CTNNBIP1-20-GOGR | 20 (40 μL) | 200 μL |
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| PUS1-CTNNBIP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PUS1-CTNNBIP1-20-GRRE | 20 (40 μL) | 200 μL |
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| PUS1-CTNNBIP1-20-GROR | 20 (40 μL) | 200 μL |
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| PUS1-CTNNBIP1-20-GRGO | 20 (40 μL) | 200 μL |
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| PUS1-CTNNBIP1-20-GRGR | 20 (40 μL) | 200 μL |
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| PUS1-CTNNBIP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PUS1-CTNNBIP1-20-AQRE | 20 (40 μL) | 200 μL |
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| PUS1-CTNNBIP1-20-AQOR | 20 (40 μL) | 200 μL |
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| PUS1-CTNNBIP1-20-AQGO | 20 (40 μL) | 200 μL |
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| PUS1-CTNNBIP1-20-AQGR | 20 (40 μL) | 200 μL |
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| PUS1-CTNNBIP1-20-AQAQ | 20 (40 μL) | 200 μL |
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CTNNBIP1 Gene Summary
The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Catenin Beta Interacting Protein 1
Chromosome: CHR1: 9908333 -9970316
Locus: 1p36.22
PUS1 Gene Summary
This gene encodes a pseudouridine synthase that converts uridine to pseudouridine once it has been incorporated into an RNA molecule. The encoded enzyme may play an essential role in tRNA function and in stabilizing the secondary and tertiary structure of many RNAs. A mutation in this gene has been linked to mitochondrial myopathy and sideroblastic anemia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2009]
Gene Name: Pseudouridylate Synthase 1
Chromosome: CHR12: 132413744 -132428406
Locus: 12q24.33
Gene Diseases
The PUS1 CTNNBIP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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