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PTPRZ1-UBE2H Fusion FISH Probe

The PTPRZ1-UBE2H Fusion FISH Probe is used to confirm a fusion of the PTPRZ1 and UBE2H genes. The fusion of the PTPRZ1 and UBE2H genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PTPRZ1-UBE2H-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
PTPRZ1-UBE2H-20-RERE 20 (40 μL) 200 μL
PTPRZ1-UBE2H-20-REOR 20 (40 μL) 200 μL
PTPRZ1-UBE2H-20-REGO 20 (40 μL) 200 μL
PTPRZ1-UBE2H-20-REGR 20 (40 μL) 200 μL
PTPRZ1-UBE2H-20-REAQ 20 (40 μL) 200 μL
PTPRZ1-UBE2H-20-ORRE 20 (40 μL) 200 μL
PTPRZ1-UBE2H-20-OROR 20 (40 μL) 200 μL
PTPRZ1-UBE2H-20-ORGO 20 (40 μL) 200 μL
PTPRZ1-UBE2H-20-ORAQ 20 (40 μL) 200 μL
PTPRZ1-UBE2H-20-GORE 20 (40 μL) 200 μL
PTPRZ1-UBE2H-20-GOOR 20 (40 μL) 200 μL
PTPRZ1-UBE2H-20-GOGO 20 (40 μL) 200 μL
PTPRZ1-UBE2H-20-GOGR 20 (40 μL) 200 μL
PTPRZ1-UBE2H-20-GOAQ 20 (40 μL) 200 μL
PTPRZ1-UBE2H-20-GRRE 20 (40 μL) 200 μL
PTPRZ1-UBE2H-20-GROR 20 (40 μL) 200 μL
PTPRZ1-UBE2H-20-GRGO 20 (40 μL) 200 μL
PTPRZ1-UBE2H-20-GRGR 20 (40 μL) 200 μL
PTPRZ1-UBE2H-20-GRAQ 20 (40 μL) 200 μL
PTPRZ1-UBE2H-20-AQRE 20 (40 μL) 200 μL
PTPRZ1-UBE2H-20-AQOR 20 (40 μL) 200 μL
PTPRZ1-UBE2H-20-AQGO 20 (40 μL) 200 μL
PTPRZ1-UBE2H-20-AQGR 20 (40 μL) 200 μL
PTPRZ1-UBE2H-20-AQAQ 20 (40 μL) 200 μL

PTPRZ1 Gene Summary

This gene encodes a member of the receptor protein tyrosine phosphatase family. Expression of this gene is restricted to the central nervous system (CNS), and it may be involved in the regulation of specific developmental processes in the CNS. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]

Gene Name: Protein Tyrosine Phosphatase, Receptor Type Z1

Chromosome: CHR7: 121513158 -121702090

Locus: 7q31.32

UBE2H Gene Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein sequence is 100% identical to the mouse homolog and 98% identical to the frog and zebrafish homologs. Three alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms. [provided by RefSeq, Feb 2011]

Gene Name: Ubiquitin Conjugating Enzyme E2 H

Chromosome: CHR7: 129470572 -129592800

Locus: 7q32.2

Gene Diseases

The PTPRZ1 UBE2H Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.