PTPRZ1-FYN Fusion FISH Probe
The PTPRZ1-FYN Fusion FISH Probe is used to confirm a fusion of the PTPRZ1 and FYN genes. The fusion of the PTPRZ1 and FYN genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PTPRZ1-FYN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PTPRZ1-FYN-20-RERE | 20 (40 μL) | 200 μL |
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| PTPRZ1-FYN-20-REOR | 20 (40 μL) | 200 μL |
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| PTPRZ1-FYN-20-REGO | 20 (40 μL) | 200 μL |
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| PTPRZ1-FYN-20-REGR | 20 (40 μL) | 200 μL |
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| PTPRZ1-FYN-20-REAQ | 20 (40 μL) | 200 μL |
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| PTPRZ1-FYN-20-ORRE | 20 (40 μL) | 200 μL |
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| PTPRZ1-FYN-20-OROR | 20 (40 μL) | 200 μL |
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| PTPRZ1-FYN-20-ORGO | 20 (40 μL) | 200 μL |
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| PTPRZ1-FYN-20-ORAQ | 20 (40 μL) | 200 μL |
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| PTPRZ1-FYN-20-GORE | 20 (40 μL) | 200 μL |
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| PTPRZ1-FYN-20-GOOR | 20 (40 μL) | 200 μL |
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| PTPRZ1-FYN-20-GOGO | 20 (40 μL) | 200 μL |
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| PTPRZ1-FYN-20-GOGR | 20 (40 μL) | 200 μL |
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| PTPRZ1-FYN-20-GOAQ | 20 (40 μL) | 200 μL |
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| PTPRZ1-FYN-20-GRRE | 20 (40 μL) | 200 μL |
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| PTPRZ1-FYN-20-GROR | 20 (40 μL) | 200 μL |
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| PTPRZ1-FYN-20-GRGO | 20 (40 μL) | 200 μL |
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| PTPRZ1-FYN-20-GRGR | 20 (40 μL) | 200 μL |
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| PTPRZ1-FYN-20-GRAQ | 20 (40 μL) | 200 μL |
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| PTPRZ1-FYN-20-AQRE | 20 (40 μL) | 200 μL |
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| PTPRZ1-FYN-20-AQOR | 20 (40 μL) | 200 μL |
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| PTPRZ1-FYN-20-AQGO | 20 (40 μL) | 200 μL |
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| PTPRZ1-FYN-20-AQGR | 20 (40 μL) | 200 μL |
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| PTPRZ1-FYN-20-AQAQ | 20 (40 μL) | 200 μL |
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FYN Gene Summary
This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist. [provided by RefSeq, Jul 2008]
Gene Name: FYN Proto-oncogene, Src Family Tyrosine Kinase
Chromosome: CHR6: 111981534 -112194655
Locus: 6q21
PTPRZ1 Gene Summary
This gene encodes a member of the receptor protein tyrosine phosphatase family. Expression of this gene is restricted to the central nervous system (CNS), and it may be involved in the regulation of specific developmental processes in the CNS. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
Gene Name: Protein Tyrosine Phosphatase, Receptor Type Z1
Chromosome: CHR7: 121513158 -121702090
Locus: 7q31.32
Gene Diseases
The PTPRZ1 FYN Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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