PTPRU-C8ORF84 Fusion FISH Probe
The PTPRU-C8ORF84 Fusion FISH Probe is used to confirm a fusion of the PTPRU and C8ORF84 genes. The fusion of the PTPRU and C8ORF84 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PTPRU-C8ORF84-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PTPRU-C8ORF84-20-RERE | 20 (40 μL) | 200 μL |
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| PTPRU-C8ORF84-20-REOR | 20 (40 μL) | 200 μL |
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| PTPRU-C8ORF84-20-REGO | 20 (40 μL) | 200 μL |
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| PTPRU-C8ORF84-20-REGR | 20 (40 μL) | 200 μL |
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| PTPRU-C8ORF84-20-REAQ | 20 (40 μL) | 200 μL |
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| PTPRU-C8ORF84-20-ORRE | 20 (40 μL) | 200 μL |
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| PTPRU-C8ORF84-20-OROR | 20 (40 μL) | 200 μL |
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| PTPRU-C8ORF84-20-ORGO | 20 (40 μL) | 200 μL |
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| PTPRU-C8ORF84-20-ORAQ | 20 (40 μL) | 200 μL |
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| PTPRU-C8ORF84-20-GORE | 20 (40 μL) | 200 μL |
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| PTPRU-C8ORF84-20-GOOR | 20 (40 μL) | 200 μL |
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| PTPRU-C8ORF84-20-GOGO | 20 (40 μL) | 200 μL |
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| PTPRU-C8ORF84-20-GOGR | 20 (40 μL) | 200 μL |
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| PTPRU-C8ORF84-20-GOAQ | 20 (40 μL) | 200 μL |
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| PTPRU-C8ORF84-20-GRRE | 20 (40 μL) | 200 μL |
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| PTPRU-C8ORF84-20-GROR | 20 (40 μL) | 200 μL |
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| PTPRU-C8ORF84-20-GRGO | 20 (40 μL) | 200 μL |
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| PTPRU-C8ORF84-20-GRGR | 20 (40 μL) | 200 μL |
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| PTPRU-C8ORF84-20-GRAQ | 20 (40 μL) | 200 μL |
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| PTPRU-C8ORF84-20-AQRE | 20 (40 μL) | 200 μL |
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| PTPRU-C8ORF84-20-AQOR | 20 (40 μL) | 200 μL |
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| PTPRU-C8ORF84-20-AQGO | 20 (40 μL) | 200 μL |
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| PTPRU-C8ORF84-20-AQGR | 20 (40 μL) | 200 μL |
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| PTPRU-C8ORF84-20-AQAQ | 20 (40 μL) | 200 μL |
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PTPRU Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Alternatively spliced transcript variants have been reported. [provided by RefSeq, Aug 2010]
Gene Name: Protein Tyrosine Phosphatase, Receptor Type U
Chromosome: CHR1: 29563027 -29653325
Locus: 1p35.3
Gene Diseases
The PTPRU C8ORF84 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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