PTPRT-EXD2 Fusion FISH Probe
The PTPRT-EXD2 Fusion FISH Probe is used to confirm a fusion of the PTPRT and EXD2 genes. The fusion of the PTPRT and EXD2 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PTPRT-EXD2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PTPRT-EXD2-20-RERE | 20 (40 μL) | 200 μL |
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| PTPRT-EXD2-20-REOR | 20 (40 μL) | 200 μL |
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| PTPRT-EXD2-20-REGO | 20 (40 μL) | 200 μL |
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| PTPRT-EXD2-20-REGR | 20 (40 μL) | 200 μL |
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| PTPRT-EXD2-20-REAQ | 20 (40 μL) | 200 μL |
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| PTPRT-EXD2-20-ORRE | 20 (40 μL) | 200 μL |
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| PTPRT-EXD2-20-OROR | 20 (40 μL) | 200 μL |
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| PTPRT-EXD2-20-ORGO | 20 (40 μL) | 200 μL |
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| PTPRT-EXD2-20-ORAQ | 20 (40 μL) | 200 μL |
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| PTPRT-EXD2-20-GORE | 20 (40 μL) | 200 μL |
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| PTPRT-EXD2-20-GOOR | 20 (40 μL) | 200 μL |
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| PTPRT-EXD2-20-GOGO | 20 (40 μL) | 200 μL |
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| PTPRT-EXD2-20-GOGR | 20 (40 μL) | 200 μL |
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| PTPRT-EXD2-20-GOAQ | 20 (40 μL) | 200 μL |
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| PTPRT-EXD2-20-GRRE | 20 (40 μL) | 200 μL |
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| PTPRT-EXD2-20-GROR | 20 (40 μL) | 200 μL |
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| PTPRT-EXD2-20-GRGO | 20 (40 μL) | 200 μL |
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| PTPRT-EXD2-20-GRGR | 20 (40 μL) | 200 μL |
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| PTPRT-EXD2-20-GRAQ | 20 (40 μL) | 200 μL |
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| PTPRT-EXD2-20-AQRE | 20 (40 μL) | 200 μL |
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| PTPRT-EXD2-20-AQOR | 20 (40 μL) | 200 μL |
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| PTPRT-EXD2-20-AQGO | 20 (40 μL) | 200 μL |
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| PTPRT-EXD2-20-AQGR | 20 (40 μL) | 200 μL |
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| PTPRT-EXD2-20-AQAQ | 20 (40 μL) | 200 μL |
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PTPRT Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of this PTP suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
Gene Name: Protein Tyrosine Phosphatase, Receptor Type T
Chromosome: CHR20: 40701391 -41818557
Locus: 20q12-q13.11
EXD2 Gene Summary
The Exonuclease 3'-5' Domain Containing 2 (EXD2) gene is located on chr14 :69658193-69710737 at 14q24.1.
Gene Name: Exonuclease 3'-5' Domain Containing 2
Chromosome: CHR14: 69658193 -69710737
Locus: 14q24.1
Gene Diseases
The PTPRT EXD2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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