PTPRS-TMEM8A Fusion FISH Probe
The PTPRS-TMEM8A Fusion FISH Probe is used to confirm a fusion of the PTPRS and TMEM8A genes. The fusion of the PTPRS and TMEM8A genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PTPRS-TMEM8A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PTPRS-TMEM8A-20-RERE | 20 (40 μL) | 200 μL |
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| PTPRS-TMEM8A-20-REOR | 20 (40 μL) | 200 μL |
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| PTPRS-TMEM8A-20-REGO | 20 (40 μL) | 200 μL |
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| PTPRS-TMEM8A-20-REGR | 20 (40 μL) | 200 μL |
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| PTPRS-TMEM8A-20-REAQ | 20 (40 μL) | 200 μL |
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| PTPRS-TMEM8A-20-ORRE | 20 (40 μL) | 200 μL |
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| PTPRS-TMEM8A-20-OROR | 20 (40 μL) | 200 μL |
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| PTPRS-TMEM8A-20-ORGO | 20 (40 μL) | 200 μL |
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| PTPRS-TMEM8A-20-ORAQ | 20 (40 μL) | 200 μL |
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| PTPRS-TMEM8A-20-GORE | 20 (40 μL) | 200 μL |
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| PTPRS-TMEM8A-20-GOOR | 20 (40 μL) | 200 μL |
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| PTPRS-TMEM8A-20-GOGO | 20 (40 μL) | 200 μL |
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| PTPRS-TMEM8A-20-GOGR | 20 (40 μL) | 200 μL |
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| PTPRS-TMEM8A-20-GOAQ | 20 (40 μL) | 200 μL |
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| PTPRS-TMEM8A-20-GRRE | 20 (40 μL) | 200 μL |
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| PTPRS-TMEM8A-20-GROR | 20 (40 μL) | 200 μL |
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| PTPRS-TMEM8A-20-GRGO | 20 (40 μL) | 200 μL |
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| PTPRS-TMEM8A-20-GRGR | 20 (40 μL) | 200 μL |
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| PTPRS-TMEM8A-20-GRAQ | 20 (40 μL) | 200 μL |
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| PTPRS-TMEM8A-20-AQRE | 20 (40 μL) | 200 μL |
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| PTPRS-TMEM8A-20-AQOR | 20 (40 μL) | 200 μL |
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| PTPRS-TMEM8A-20-AQGO | 20 (40 μL) | 200 μL |
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| PTPRS-TMEM8A-20-AQGR | 20 (40 μL) | 200 μL |
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| PTPRS-TMEM8A-20-AQAQ | 20 (40 μL) | 200 μL |
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PTPRS Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
Gene Name: Protein Tyrosine Phosphatase, Receptor Type S
Chromosome: CHR19: 5205518 -5340814
Locus: 19p13.3
TMEM8A Gene Summary
The Transmembrane Protein 8A (TMEM8A) gene is located on chr16 :420775-431950 at 16p13.3.
Gene Name: Transmembrane Protein 8A
Chromosome: CHR16: 420775 -431950
Locus: 16p13.3
Gene Diseases
The PTPRS TMEM8A Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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