PTPRR-VWC2 Fusion FISH Probe
The PTPRR-VWC2 Fusion FISH Probe is used to confirm a fusion of the PTPRR and VWC2 genes. The fusion of the PTPRR and VWC2 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PTPRR-VWC2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PTPRR-VWC2-20-RERE | 20 (40 μL) | 200 μL |
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| PTPRR-VWC2-20-REOR | 20 (40 μL) | 200 μL |
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| PTPRR-VWC2-20-REGO | 20 (40 μL) | 200 μL |
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| PTPRR-VWC2-20-REGR | 20 (40 μL) | 200 μL |
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| PTPRR-VWC2-20-REAQ | 20 (40 μL) | 200 μL |
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| PTPRR-VWC2-20-ORRE | 20 (40 μL) | 200 μL |
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| PTPRR-VWC2-20-OROR | 20 (40 μL) | 200 μL |
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| PTPRR-VWC2-20-ORGO | 20 (40 μL) | 200 μL |
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| PTPRR-VWC2-20-ORAQ | 20 (40 μL) | 200 μL |
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| PTPRR-VWC2-20-GORE | 20 (40 μL) | 200 μL |
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| PTPRR-VWC2-20-GOOR | 20 (40 μL) | 200 μL |
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| PTPRR-VWC2-20-GOGO | 20 (40 μL) | 200 μL |
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| PTPRR-VWC2-20-GOGR | 20 (40 μL) | 200 μL |
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| PTPRR-VWC2-20-GOAQ | 20 (40 μL) | 200 μL |
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| PTPRR-VWC2-20-GRRE | 20 (40 μL) | 200 μL |
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| PTPRR-VWC2-20-GROR | 20 (40 μL) | 200 μL |
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| PTPRR-VWC2-20-GRGO | 20 (40 μL) | 200 μL |
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| PTPRR-VWC2-20-GRGR | 20 (40 μL) | 200 μL |
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| PTPRR-VWC2-20-GRAQ | 20 (40 μL) | 200 μL |
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| PTPRR-VWC2-20-AQRE | 20 (40 μL) | 200 μL |
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| PTPRR-VWC2-20-AQOR | 20 (40 μL) | 200 μL |
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| PTPRR-VWC2-20-AQGO | 20 (40 μL) | 200 μL |
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| PTPRR-VWC2-20-AQGR | 20 (40 μL) | 200 μL |
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| PTPRR-VWC2-20-AQAQ | 20 (40 μL) | 200 μL |
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PTPRR Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12. [provided by RefSeq, May 2011]
Gene Name: Protein Tyrosine Phosphatase, Receptor Type R
Chromosome: CHR12: 71031852 -71314584
Locus: 12q15
VWC2 Gene Summary
This gene encodes a secreted bone morphogenic protein antagonist. The encoded protein is possibly involved in neural function and development and may have a role in cell adhesion.[provided by RefSeq, Oct 2009]
Gene Name: Von Willebrand Factor C Domain Containing 2
Chromosome: CHR7: 49813256 -49952138
Locus: 7p12.2
Gene Diseases
The PTPRR VWC2 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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