PTPRR-KCNC2 Fusion FISH Probe
The PTPRR-KCNC2 Fusion FISH Probe is used to confirm a fusion of the PTPRR and KCNC2 genes. The fusion of the PTPRR and KCNC2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PTPRR-KCNC2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PTPRR-KCNC2-20-RERE | 20 (40 μL) | 200 μL |
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| PTPRR-KCNC2-20-REOR | 20 (40 μL) | 200 μL |
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| PTPRR-KCNC2-20-REGO | 20 (40 μL) | 200 μL |
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| PTPRR-KCNC2-20-REGR | 20 (40 μL) | 200 μL |
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| PTPRR-KCNC2-20-REAQ | 20 (40 μL) | 200 μL |
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| PTPRR-KCNC2-20-ORRE | 20 (40 μL) | 200 μL |
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| PTPRR-KCNC2-20-OROR | 20 (40 μL) | 200 μL |
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| PTPRR-KCNC2-20-ORGO | 20 (40 μL) | 200 μL |
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| PTPRR-KCNC2-20-ORAQ | 20 (40 μL) | 200 μL |
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| PTPRR-KCNC2-20-GORE | 20 (40 μL) | 200 μL |
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| PTPRR-KCNC2-20-GOOR | 20 (40 μL) | 200 μL |
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| PTPRR-KCNC2-20-GOGO | 20 (40 μL) | 200 μL |
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| PTPRR-KCNC2-20-GOGR | 20 (40 μL) | 200 μL |
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| PTPRR-KCNC2-20-GOAQ | 20 (40 μL) | 200 μL |
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| PTPRR-KCNC2-20-GRRE | 20 (40 μL) | 200 μL |
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| PTPRR-KCNC2-20-GROR | 20 (40 μL) | 200 μL |
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| PTPRR-KCNC2-20-GRGO | 20 (40 μL) | 200 μL |
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| PTPRR-KCNC2-20-GRGR | 20 (40 μL) | 200 μL |
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| PTPRR-KCNC2-20-GRAQ | 20 (40 μL) | 200 μL |
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| PTPRR-KCNC2-20-AQRE | 20 (40 μL) | 200 μL |
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| PTPRR-KCNC2-20-AQOR | 20 (40 μL) | 200 μL |
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| PTPRR-KCNC2-20-AQGO | 20 (40 μL) | 200 μL |
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| PTPRR-KCNC2-20-AQGR | 20 (40 μL) | 200 μL |
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| PTPRR-KCNC2-20-AQAQ | 20 (40 μL) | 200 μL |
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KCNC2 Gene Summary
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
Gene Name: Potassium Voltage-gated Channel Subfamily C Member 2
Chromosome: CHR12: 75433895 -75603511
Locus: 12q21.1
PTPRR Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12. [provided by RefSeq, May 2011]
Gene Name: Protein Tyrosine Phosphatase, Receptor Type R
Chromosome: CHR12: 71031852 -71314584
Locus: 12q15
Gene Diseases
The PTPRR KCNC2 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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