PTPRN2-LRRC37B Fusion FISH Probe
The PTPRN2-LRRC37B Fusion FISH Probe is used to confirm a fusion of the PTPRN2 and LRRC37B genes. The fusion of the PTPRN2 and LRRC37B genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PTPRN2-LRRC37B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PTPRN2-LRRC37B-20-RERE | 20 (40 μL) | 200 μL |
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| PTPRN2-LRRC37B-20-REOR | 20 (40 μL) | 200 μL |
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| PTPRN2-LRRC37B-20-REGO | 20 (40 μL) | 200 μL |
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| PTPRN2-LRRC37B-20-REGR | 20 (40 μL) | 200 μL |
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| PTPRN2-LRRC37B-20-REAQ | 20 (40 μL) | 200 μL |
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| PTPRN2-LRRC37B-20-ORRE | 20 (40 μL) | 200 μL |
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| PTPRN2-LRRC37B-20-OROR | 20 (40 μL) | 200 μL |
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| PTPRN2-LRRC37B-20-ORGO | 20 (40 μL) | 200 μL |
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| PTPRN2-LRRC37B-20-ORAQ | 20 (40 μL) | 200 μL |
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| PTPRN2-LRRC37B-20-GORE | 20 (40 μL) | 200 μL |
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| PTPRN2-LRRC37B-20-GOOR | 20 (40 μL) | 200 μL |
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| PTPRN2-LRRC37B-20-GOGO | 20 (40 μL) | 200 μL |
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| PTPRN2-LRRC37B-20-GOGR | 20 (40 μL) | 200 μL |
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| PTPRN2-LRRC37B-20-GOAQ | 20 (40 μL) | 200 μL |
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| PTPRN2-LRRC37B-20-GRRE | 20 (40 μL) | 200 μL |
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| PTPRN2-LRRC37B-20-GROR | 20 (40 μL) | 200 μL |
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| PTPRN2-LRRC37B-20-GRGO | 20 (40 μL) | 200 μL |
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| PTPRN2-LRRC37B-20-GRGR | 20 (40 μL) | 200 μL |
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| PTPRN2-LRRC37B-20-GRAQ | 20 (40 μL) | 200 μL |
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| PTPRN2-LRRC37B-20-AQRE | 20 (40 μL) | 200 μL |
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| PTPRN2-LRRC37B-20-AQOR | 20 (40 μL) | 200 μL |
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| PTPRN2-LRRC37B-20-AQGO | 20 (40 μL) | 200 μL |
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| PTPRN2-LRRC37B-20-AQGR | 20 (40 μL) | 200 μL |
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| PTPRN2-LRRC37B-20-AQAQ | 20 (40 μL) | 200 μL |
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PTPRN2 Gene Summary
This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Gene Name: Protein Tyrosine Phosphatase, Receptor Type N2
Chromosome: CHR7: 157331749 -158380482
Locus: 7q36.3
LRRC37B Gene Summary
The Leucine Rich Repeat Containing 37B (LRRC37B) gene is located on chr17 :30348154-30380519 at 17q11.2.
Gene Name: Leucine Rich Repeat Containing 37B
Chromosome: CHR17: 30348154 -30380519
Locus: 17q11.2
Gene Diseases
The PTPRN2 LRRC37B Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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