PTPRJ-PPP2CB Fusion FISH Probe
The PTPRJ-PPP2CB Fusion FISH Probe is used to confirm a fusion of the PTPRJ and PPP2CB genes. The fusion of the PTPRJ and PPP2CB genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PTPRJ-PPP2CB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PTPRJ-PPP2CB-20-RERE | 20 (40 μL) | 200 μL |
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| PTPRJ-PPP2CB-20-REOR | 20 (40 μL) | 200 μL |
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| PTPRJ-PPP2CB-20-REGO | 20 (40 μL) | 200 μL |
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| PTPRJ-PPP2CB-20-REGR | 20 (40 μL) | 200 μL |
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| PTPRJ-PPP2CB-20-REAQ | 20 (40 μL) | 200 μL |
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| PTPRJ-PPP2CB-20-ORRE | 20 (40 μL) | 200 μL |
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| PTPRJ-PPP2CB-20-OROR | 20 (40 μL) | 200 μL |
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| PTPRJ-PPP2CB-20-ORGO | 20 (40 μL) | 200 μL |
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| PTPRJ-PPP2CB-20-ORAQ | 20 (40 μL) | 200 μL |
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| PTPRJ-PPP2CB-20-GORE | 20 (40 μL) | 200 μL |
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| PTPRJ-PPP2CB-20-GOOR | 20 (40 μL) | 200 μL |
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| PTPRJ-PPP2CB-20-GOGO | 20 (40 μL) | 200 μL |
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| PTPRJ-PPP2CB-20-GOGR | 20 (40 μL) | 200 μL |
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| PTPRJ-PPP2CB-20-GOAQ | 20 (40 μL) | 200 μL |
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| PTPRJ-PPP2CB-20-GRRE | 20 (40 μL) | 200 μL |
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| PTPRJ-PPP2CB-20-GROR | 20 (40 μL) | 200 μL |
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| PTPRJ-PPP2CB-20-GRGO | 20 (40 μL) | 200 μL |
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| PTPRJ-PPP2CB-20-GRGR | 20 (40 μL) | 200 μL |
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| PTPRJ-PPP2CB-20-GRAQ | 20 (40 μL) | 200 μL |
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| PTPRJ-PPP2CB-20-AQRE | 20 (40 μL) | 200 μL |
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| PTPRJ-PPP2CB-20-AQOR | 20 (40 μL) | 200 μL |
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| PTPRJ-PPP2CB-20-AQGO | 20 (40 μL) | 200 μL |
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| PTPRJ-PPP2CB-20-AQGR | 20 (40 μL) | 200 μL |
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| PTPRJ-PPP2CB-20-AQAQ | 20 (40 μL) | 200 μL |
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PPP2CB Gene Summary
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. [provided by RefSeq, Mar 2010]
Gene Name: Protein Phosphatase 2 Catalytic Subunit Beta
Chromosome: CHR8: 30643125 -30670352
Locus: 8p12
PTPRJ Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Protein Tyrosine Phosphatase, Receptor Type J
Chromosome: CHR11: 48002109 -48192394
Locus: 11p11.2
Gene Diseases
The PTPRJ PPP2CB Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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