PTPRG-FRMD4B Fusion FISH Probe
The PTPRG-FRMD4B Fusion FISH Probe is used to confirm a fusion of the PTPRG and FRMD4B genes. The fusion of the PTPRG and FRMD4B genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PTPRG-FRMD4B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PTPRG-FRMD4B-20-RERE | 20 (40 μL) | 200 μL |
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| PTPRG-FRMD4B-20-REOR | 20 (40 μL) | 200 μL |
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| PTPRG-FRMD4B-20-REGO | 20 (40 μL) | 200 μL |
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| PTPRG-FRMD4B-20-REGR | 20 (40 μL) | 200 μL |
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| PTPRG-FRMD4B-20-REAQ | 20 (40 μL) | 200 μL |
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| PTPRG-FRMD4B-20-ORRE | 20 (40 μL) | 200 μL |
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| PTPRG-FRMD4B-20-OROR | 20 (40 μL) | 200 μL |
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| PTPRG-FRMD4B-20-ORGO | 20 (40 μL) | 200 μL |
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| PTPRG-FRMD4B-20-ORAQ | 20 (40 μL) | 200 μL |
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| PTPRG-FRMD4B-20-GORE | 20 (40 μL) | 200 μL |
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| PTPRG-FRMD4B-20-GOOR | 20 (40 μL) | 200 μL |
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| PTPRG-FRMD4B-20-GOGO | 20 (40 μL) | 200 μL |
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| PTPRG-FRMD4B-20-GOGR | 20 (40 μL) | 200 μL |
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| PTPRG-FRMD4B-20-GOAQ | 20 (40 μL) | 200 μL |
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| PTPRG-FRMD4B-20-GRRE | 20 (40 μL) | 200 μL |
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| PTPRG-FRMD4B-20-GROR | 20 (40 μL) | 200 μL |
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| PTPRG-FRMD4B-20-GRGO | 20 (40 μL) | 200 μL |
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| PTPRG-FRMD4B-20-GRGR | 20 (40 μL) | 200 μL |
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| PTPRG-FRMD4B-20-GRAQ | 20 (40 μL) | 200 μL |
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| PTPRG-FRMD4B-20-AQRE | 20 (40 μL) | 200 μL |
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| PTPRG-FRMD4B-20-AQOR | 20 (40 μL) | 200 μL |
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| PTPRG-FRMD4B-20-AQGO | 20 (40 μL) | 200 μL |
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| PTPRG-FRMD4B-20-AQGR | 20 (40 μL) | 200 μL |
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| PTPRG-FRMD4B-20-AQAQ | 20 (40 μL) | 200 μL |
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PTPRG Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene. [provided by RefSeq, Jul 2008]
Gene Name: Protein Tyrosine Phosphatase, Receptor Type G
Chromosome: CHR3: 61547242 -62280573
Locus: 3p14.2
FRMD4B Gene Summary
This gene encodes a GRP1-binding protein which contains a FERM protein interaction domain as well as two coiled coil domains. This protein may play a role as a scaffolding protein. [provided by RefSeq, Mar 2014]
Gene Name: FERM Domain Containing 4B
Chromosome: CHR3: 69219145 -69435430
Locus: 3p14.1
Gene Diseases
The PTPRG FRMD4B Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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