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PTPRF-DHRS4L2 Fusion FISH Probe

The PTPRF-DHRS4L2 Fusion FISH Probe is used to confirm a fusion of the PTPRF and DHRS4L2 genes. The fusion of the PTPRF and DHRS4L2 genes has been associated with Rectum Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PTPRF-DHRS4L2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
PTPRF-DHRS4L2-20-RERE 20 (40 μL) 200 μL
PTPRF-DHRS4L2-20-REOR 20 (40 μL) 200 μL
PTPRF-DHRS4L2-20-REGO 20 (40 μL) 200 μL
PTPRF-DHRS4L2-20-REGR 20 (40 μL) 200 μL
PTPRF-DHRS4L2-20-REAQ 20 (40 μL) 200 μL
PTPRF-DHRS4L2-20-ORRE 20 (40 μL) 200 μL
PTPRF-DHRS4L2-20-OROR 20 (40 μL) 200 μL
PTPRF-DHRS4L2-20-ORGO 20 (40 μL) 200 μL
PTPRF-DHRS4L2-20-ORAQ 20 (40 μL) 200 μL
PTPRF-DHRS4L2-20-GORE 20 (40 μL) 200 μL
PTPRF-DHRS4L2-20-GOOR 20 (40 μL) 200 μL
PTPRF-DHRS4L2-20-GOGO 20 (40 μL) 200 μL
PTPRF-DHRS4L2-20-GOGR 20 (40 μL) 200 μL
PTPRF-DHRS4L2-20-GOAQ 20 (40 μL) 200 μL
PTPRF-DHRS4L2-20-GRRE 20 (40 μL) 200 μL
PTPRF-DHRS4L2-20-GROR 20 (40 μL) 200 μL
PTPRF-DHRS4L2-20-GRGO 20 (40 μL) 200 μL
PTPRF-DHRS4L2-20-GRGR 20 (40 μL) 200 μL
PTPRF-DHRS4L2-20-GRAQ 20 (40 μL) 200 μL
PTPRF-DHRS4L2-20-AQRE 20 (40 μL) 200 μL
PTPRF-DHRS4L2-20-AQOR 20 (40 μL) 200 μL
PTPRF-DHRS4L2-20-AQGO 20 (40 μL) 200 μL
PTPRF-DHRS4L2-20-AQGR 20 (40 μL) 200 μL
PTPRF-DHRS4L2-20-AQAQ 20 (40 μL) 200 μL

PTPRF Gene Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]

Gene Name: Protein Tyrosine Phosphatase, Receptor Type F

Chromosome: CHR1: 43996546 -44089343

Locus: 1p34.2

DHRS4L2 Gene Summary

This gene encodes a member of the short chain dehydrogenase reductase family. The encoded protein may be an NADPH dependent retinol oxidoreductase. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]

Gene Name: Dehydrogenase/reductase 4 Like 2

Chromosome: CHR14: 24439082 -24475617

Locus: 14q11.2

Gene Diseases

The PTPRF DHRS4L2 Fusion has been associated with the following diseases:

Disease Name
Rectum Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.