PTPRF-DHRS4L2 Fusion FISH Probe
The PTPRF-DHRS4L2 Fusion FISH Probe is used to confirm a fusion of the PTPRF and DHRS4L2 genes. The fusion of the PTPRF and DHRS4L2 genes has been associated with Rectum Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PTPRF-DHRS4L2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PTPRF-DHRS4L2-20-RERE | 20 (40 μL) | 200 μL |
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| PTPRF-DHRS4L2-20-REOR | 20 (40 μL) | 200 μL |
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| PTPRF-DHRS4L2-20-REGO | 20 (40 μL) | 200 μL |
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| PTPRF-DHRS4L2-20-REGR | 20 (40 μL) | 200 μL |
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| PTPRF-DHRS4L2-20-REAQ | 20 (40 μL) | 200 μL |
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| PTPRF-DHRS4L2-20-ORRE | 20 (40 μL) | 200 μL |
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| PTPRF-DHRS4L2-20-OROR | 20 (40 μL) | 200 μL |
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| PTPRF-DHRS4L2-20-ORGO | 20 (40 μL) | 200 μL |
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| PTPRF-DHRS4L2-20-ORAQ | 20 (40 μL) | 200 μL |
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| PTPRF-DHRS4L2-20-GORE | 20 (40 μL) | 200 μL |
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| PTPRF-DHRS4L2-20-GOOR | 20 (40 μL) | 200 μL |
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| PTPRF-DHRS4L2-20-GOGO | 20 (40 μL) | 200 μL |
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| PTPRF-DHRS4L2-20-GOGR | 20 (40 μL) | 200 μL |
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| PTPRF-DHRS4L2-20-GOAQ | 20 (40 μL) | 200 μL |
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| PTPRF-DHRS4L2-20-GRRE | 20 (40 μL) | 200 μL |
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| PTPRF-DHRS4L2-20-GROR | 20 (40 μL) | 200 μL |
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| PTPRF-DHRS4L2-20-GRGO | 20 (40 μL) | 200 μL |
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| PTPRF-DHRS4L2-20-GRGR | 20 (40 μL) | 200 μL |
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| PTPRF-DHRS4L2-20-GRAQ | 20 (40 μL) | 200 μL |
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| PTPRF-DHRS4L2-20-AQRE | 20 (40 μL) | 200 μL |
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| PTPRF-DHRS4L2-20-AQOR | 20 (40 μL) | 200 μL |
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| PTPRF-DHRS4L2-20-AQGO | 20 (40 μL) | 200 μL |
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| PTPRF-DHRS4L2-20-AQGR | 20 (40 μL) | 200 μL |
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| PTPRF-DHRS4L2-20-AQAQ | 20 (40 μL) | 200 μL |
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PTPRF Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
Gene Name: Protein Tyrosine Phosphatase, Receptor Type F
Chromosome: CHR1: 43996546 -44089343
Locus: 1p34.2
DHRS4L2 Gene Summary
This gene encodes a member of the short chain dehydrogenase reductase family. The encoded protein may be an NADPH dependent retinol oxidoreductase. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]
Gene Name: Dehydrogenase/reductase 4 Like 2
Chromosome: CHR14: 24439082 -24475617
Locus: 14q11.2
Gene Diseases
The PTPRF DHRS4L2 Fusion has been associated with the following diseases:
| Disease Name |
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| Rectum Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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