PTPRA-N4BP1 Fusion FISH Probe
The PTPRA-N4BP1 Fusion FISH Probe is used to confirm a fusion of the PTPRA and N4BP1 genes. The fusion of the PTPRA and N4BP1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PTPRA-N4BP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PTPRA-N4BP1-20-RERE | 20 (40 μL) | 200 μL |
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| PTPRA-N4BP1-20-REOR | 20 (40 μL) | 200 μL |
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| PTPRA-N4BP1-20-REGO | 20 (40 μL) | 200 μL |
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| PTPRA-N4BP1-20-REGR | 20 (40 μL) | 200 μL |
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| PTPRA-N4BP1-20-REAQ | 20 (40 μL) | 200 μL |
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| PTPRA-N4BP1-20-ORRE | 20 (40 μL) | 200 μL |
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| PTPRA-N4BP1-20-OROR | 20 (40 μL) | 200 μL |
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| PTPRA-N4BP1-20-ORGO | 20 (40 μL) | 200 μL |
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| PTPRA-N4BP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PTPRA-N4BP1-20-GORE | 20 (40 μL) | 200 μL |
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| PTPRA-N4BP1-20-GOOR | 20 (40 μL) | 200 μL |
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| PTPRA-N4BP1-20-GOGO | 20 (40 μL) | 200 μL |
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| PTPRA-N4BP1-20-GOGR | 20 (40 μL) | 200 μL |
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| PTPRA-N4BP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PTPRA-N4BP1-20-GRRE | 20 (40 μL) | 200 μL |
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| PTPRA-N4BP1-20-GROR | 20 (40 μL) | 200 μL |
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| PTPRA-N4BP1-20-GRGO | 20 (40 μL) | 200 μL |
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| PTPRA-N4BP1-20-GRGR | 20 (40 μL) | 200 μL |
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| PTPRA-N4BP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PTPRA-N4BP1-20-AQRE | 20 (40 μL) | 200 μL |
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| PTPRA-N4BP1-20-AQOR | 20 (40 μL) | 200 μL |
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| PTPRA-N4BP1-20-AQGO | 20 (40 μL) | 200 μL |
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| PTPRA-N4BP1-20-AQGR | 20 (40 μL) | 200 μL |
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| PTPRA-N4BP1-20-AQAQ | 20 (40 μL) | 200 μL |
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PTPRA Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]
Gene Name: Protein Tyrosine Phosphatase, Receptor Type A
Chromosome: CHR20: 2844840 -3019315
Locus: 20p13
N4BP1 Gene Summary
The NEDD4 Binding Protein 1 (N4BP1) gene is located on chr16 :48572636-48644120 at 16q12.1.
Gene Name: NEDD4 Binding Protein 1
Chromosome: CHR16: 48572636 -48644120
Locus: 16q12.1
Gene Diseases
The PTPRA N4BP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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